Azure A eosinate
Azure A eosinate structure
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Common Name | Azure A eosinate | ||
|---|---|---|---|---|
| CAS Number | 62298-43-5 | Molecular Weight | 291.79900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H14ClN3S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
Bioorg. Med. Chem. Lett. 19 , 4952-7, (2009) Aggregated amyloid-beta (Abeta) peptide is implicated in the pathology of Alzheimer's disease. In vitro and in vivo, these aggregates are found in a variety of morphologies, including globular oligomers and linear fibrils, which possess distinct biological ac... |
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Ligand polarizability contributes to tau fibril binding affinity.
Bioorg. Med. Chem. 19 , 5147-54, (2011) Whole brain imaging of tau-bearing neurofibrillary lesions has the potential to improve the premortem diagnosis and staging of Alzheimer's disease. Diverse compounds with high affinity for tau aggregates have been reported from high-throughput screens, but th... |
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