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3-(carbamoylamino)-2-methyl-propanoic acid

3-(carbamoylamino)-2-methyl-propanoic acid结构式
3-(carbamoylamino)-2-methyl-propanoic acid结构式
委托求购
常用名 3-(carbamoylamino)-2-methyl-propanoic acid 英文名 3-(carbamoylamino)-2-methyl-propanoic acid
CAS号 2905-86-4 分子量 146.14400
密度 1.263g/cm3 沸点 317.5ºC at 760mmHg
分子式 C5H10N2O3 熔点 N/A
MSDS 美版 闪点 145.8ºC
符号 GHS05
GHS05
信号词 Danger

beta-Ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities.

Hum. Mol. Genet. 13(22) , 2793-801, (2004)

beta-Ureidopropionase deficiency is an inborn error of the pyrimidine degradation pathway, affecting the cleavage of N-carbamyl-beta-alanine and N-carbamyl-beta-aminoisobutyric acid. In this study, we report the elucidation of the genetic basis underlying a b...

Sensitive method for the quantification of urinary pyrimidine metabolites in healthy adults by gas chromatography-tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 791(1-2) , 371-80, (2003)

Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil. To assess whether urinary levels of pyrimidines and their metabolites can be used for predicting patients' individual ...

Screening and diagnosis of beta-ureidopropionase deficiency by gas chromatographic/mass spectrometric analysis of urine.

J. Mass Spectrom. 37(9) , 954-62, (2002)

Dihydropyrimidine dehydrogenase (DHPDase), dihydropyrimidinase (DHPase) and beta-ureidopropionase (betaUPase) are the enzymes that catalyze the first, second, and third steps of the degradation of pyrimidines, respectively. beta-Ureidopropionate (betaUP) and ...