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5-溴吲哚

5-溴吲哚结构式
5-溴吲哚结构式
品牌特惠专场
常用名 5-溴吲哚 英文名 5-Bromoindole
CAS号 10075-50-0 分子量 196.044
密度 1.7±0.1 g/cm3 沸点 316.9±15.0 °C at 760 mmHg
分子式 C8H6BrN 熔点 90-92 °C(lit.)
MSDS 中文版 美版 闪点 145.5±20.4 °C
符号 GHS07
GHS07
信号词 Warning

Identification of novel CYP2A6 inhibitors by virtual screening

Bioorg. Med. Chem. 19 , 7186-93, (2011)

The human CYP2A6 enzyme metabolises several xenobiotics including nicotine, the addictive component in tobacco. Reduced activity of CYP2A6, either for genetic reasons or by administering inhibitors of CYP2A6, reduces tobacco smoking. The aim was to design nov...

Rational design of novel CYP2A6 inhibitors.

Bioorg. Med. Chem. 22(23) , 6655-64, (2015)

Inhibition of CYP2A6-mediated nicotine metabolism can reduce cigarette smoking. We sought potent and selective CYP2A6 inhibitors to be used as leads for drugs useful in smoking reduction therapy, by evaluating CYP2A6 inhibitory effect of novel formyl, alkyl a...

Untargeted Screening and Distribution of Organo-Bromine Compounds in Sediments of Lake Michigan.

Environ. Sci. Technol. 50 , 321-30, (2016)

Previously unreported natural and synthetic organo-bromine compounds (NSOBCs) have been found to contribute more than 99% of total organic bromine (TOB) in environmental matrices. We recently developed a novel untargeted method (data-independent precursor iso...