2-氨基-4-羟基蝶啶
2-氨基-4-羟基蝶啶结构式
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常用名 | 2-氨基-4-羟基蝶啶 | 英文名 | 2-Amino-1,5-dihydropteridin-4-ol |
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| CAS号 | 2236-60-4 | 分子量 | 163.13700 | |
| 密度 | 1.91g/cm3 | 沸点 | 424.7ºC at 760mmHg | |
| 分子式 | C6H5N5O | 熔点 | 300 °C | |
| MSDS | 中文版 美版 | 闪点 | 210.7ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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In Vitro and In Vivo Analysis of the Gram-Negative Bacteria-Derived Riboflavin Precursor Derivatives Activating Mouse MAIT Cells.
J. Immunol. 194 , 4641-9, (2015) Mucosal-associated invariant T (MAIT) cells recognize microbial compounds presented by the MHC-related 1 (MR1) protein. Although riboflavin precursor derivatives from Gram-positive bacteria have been characterized, some level of ligand heterogeneity has been ... |
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Least absolute shrinkage and selection operator and dimensionality reduction techniques in quantitative structure retention relationship modeling of retention in hydrophilic interaction liquid chromatography.
J. Chromatogr. A. 1403 , 54-62, (2015) The objective of this study was to model the retention of nucleosides and pterins in hydrophilic interaction liquid chromatography (HILIC) via QSRR-based approach. Two home-made (Amino-P-C18, Amino-P-C10) and one commercial (IAM.PC.DD2) HILIC stationary phase... |
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Normalization of urinary pteridines by urine specific gravity for early cancer detection.
Clin. Chim. Acta 435 , 42-7, (2014) Urinary biomarkers, such as pteridines, require normalization with respect to an individual's hydration status and time since last urination. Conventional creatinine-based corrections are affected by a multitude of patient factors whereas urine specific gravi... |
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Direct radical scavenging activity of benzbromarone provides beneficial antioxidant properties for hyperuricemia treatment.
Biol. Pharm. Bull. 38(3) , 487-92, (2015) Uric acid exerts an important antioxidant effect against external oxidative stress under physiological conditions. However, uric acid itself can increase oxidative stress via reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activation in ad... |
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Impaired systemic tetrahydrobiopterin bioavailability and increased oxidized biopterins in pediatric falciparum malaria: association with disease severity.
PLoS Pathog. 11(3) , e1004655, (2015) Decreased bioavailability of nitric oxide (NO) is a major contributor to the pathophysiology of severe falciparum malaria. Tetrahydrobiopterin (BH4) is an enzyme cofactor required for NO synthesis from L-arginine. We hypothesized that systemic levels of BH₄ w... |
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Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin.
Annu. Rev. Biochem. 54 , 729, (1985)
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Lethal mutations induced in Drosophila melanogaster by direct or indirect action of pteridines.
Mutat. Res. 128(2) , 147-52, (1984) The experiments described in this paper show that synthetic pteridines, especially biopterin and pterin, injected directly into Drosophila melanogaster induce recessive lethals. On the contrary, D-neopterin seems to have little effect. A mutagenic effect has ... |
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Inhibition of mammalian xanthine oxidase by folate compounds and amethopterin.
J. Biol. Chem. 259(1) , 12-5, (1984) We have examined the effects of folate compounds and the folate analog amethopterin (methotrexate) as inhibitors of mammalian xanthine oxidase and have found that they offer potent inhibition of the enzyme. We have compared the inhibitory potency of folic aci... |
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Efficacy of the Ketogenic Diet for the Treatment of Refractory Childhood Epilepsy: Cerebrospinal Fluid Neurotransmitters and Amino Acid Levels.
Pediatr. Neurol. 53 , 422-6, (2015) The mechanisms of the ketogenic diet remain unclear, but several predictors of response have been proposed. We aimed is to study the relationship between the etiology of epilepsy, cerebrospinal fluid neurotransmitters, pterins, and amino acids, and response t... |