焦碳酸二甲酯(DMPC)
焦碳酸二甲酯(DMPC)结构式
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常用名 | 焦碳酸二甲酯(DMPC) | 英文名 | Velcorin |
|---|---|---|---|---|
| CAS号 | 4525-33-1 | 分子量 | 134.087 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 171.4±0.0 °C at 760 mmHg | |
| 分子式 | C4H6O5 | 熔点 | 15-17ºC | |
| MSDS | 中文版 美版 | 闪点 | 80.0±0.0 °C | |
| 符号 |
GHS05, GHS06 |
信号词 | Danger |
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Influence of the lipid membrane environment on structure and activity of the outer membrane protein Ail from Yersinia pestis.
Biochim. Biophys. Acta 1848(2) , 712-20, (2014) The surrounding environment has significant consequences for the structural and functional properties of membrane proteins. While native structure and function can be reconstituted in lipid bilayer membranes, the detergents used for protein solubilization are... |
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Investigating the role of GXXXG motifs in helical folding and self-association of plasticins, Gly/Leu-rich antimicrobial peptides.
Biophys. Chem. 196 , 40-52, (2014) Plasticins (PTC) are dermaseptin-related antimicrobial peptides characterized by a large number of leucine and glycine residues arranged in GXXXG motifs that are often described to promote helix association within biological membranes. We report the structure... |
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Comparison of [corrected] actin- and glass-supported phospholipid bilayer diffusion coefficients.
Biophys. J. 108(8) , 1946-53, (2015) The formation of biomimetic lipid membranes has the potential to provide insights into cellular lipid membrane dynamics. The construction of such membranes necessitates not only the utilization of appropriate lipids, but also physiologically relevant substrat... |
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Characterizing the structure of lipodisq nanoparticles for membrane protein spectroscopic studies.
Biochim. Biophys. Acta 1848(1 Pt B) , 329-33, (2015) Membrane protein spectroscopic studies are challenging due to the difficulty introduced in preparing homogenous and functional hydrophobic proteins incorporated into a lipid bilayer system. Traditional membrane mimics such as micelles or liposomes have proved... |
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Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1).
PLoS ONE 10 , e0141252, (2015) Cytochrome P450c17 (P450 17A1, CYP17A1) is a critical enzyme in the synthesis of androgens and is now a target enzyme for the treatment of prostate cancer. Cytochrome P450c17 can exhibit either one or two physiological enzymatic activities differentially regu... |
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Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78.
Biochim. Biophys. Acta 1848(5) , 1139-46, (2015) Antimicrobial peptides (AMPs) are a class of broad-spectrum antibiotics known by their ability to disrupt bacterial membranes and their low tendency to induce bacterial resistance, arising as excellent candidates to fight bacterial infections. In this study w... |
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Control and role of pH in peptide-lipid interactions in oriented membrane samples.
Biochim. Biophys. Acta 1848(3) , 833-41, (2015) To understand the molecular mechanisms of amphiphilic membrane-active peptides, one needs to study their interactions with lipid bilayers under ambient conditions. However, it is difficult to control the pH of the sample in biophysical experiments that make u... |
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Reversible phospholipid nanogels for deoxyribonucleic acid fragment size determinations up to 1500 base pairs and integrated sample stacking.
Anal. Chim. Acta 880 , 136-44, (2015) Phospholipid additives are a cost-effective medium to separate deoxyribonucleic acid (DNA) fragments and possess a thermally-responsive viscosity. This provides a mechanism to easily create and replace a highly viscous nanogel in a narrow bore capillary with ... |
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Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactions.
Sci. Rep. 5 , 15916, (2015) Prenylated proteins play key roles in several human diseases including cancer, atherosclerosis and Alzheimer's disease. KRAS4b, which is frequently mutated in pancreatic, colon and lung cancers, is processed by farnesylation, proteolytic cleavage and carboxym... |
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NMR-based molecular ruler for determining the depth of intercalants within the lipid bilayer. Part IV: studies on ketophospholipids.
Chem. Phys. Lipids 184 , 119-28, (2014) In our companion paper, we described the preparation and intercalation of two homologous series of dicarbonyl compounds, methyl n-oxooctadecanoates and the corresponding n-oxooctadecanoic acids (n=4-16), into DMPC liposomes. (13)C NMR chemical shift of the va... |