3-氨基丙烷-1-磷酸
3-氨基丙烷-1-磷酸结构式
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常用名 | 3-氨基丙烷-1-磷酸 | 英文名 | 3-Aminopropylphosphonic acid |
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| CAS号 | 13138-33-5 | 分子量 | 139.090 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 343.0±44.0 °C at 760 mmHg | |
| 分子式 | C3H10NO3P | 熔点 | 290-294ºC | |
| MSDS | 中文版 美版 | 闪点 | 161.2±28.4 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Activation of GABA B receptors in the anterior pituitary inhibits prolactin and luteinizing hormone secretion.
Neuroendocrinology 56 , 687, (1992) Previous work from our laboratory showed that baclofen could lower serum prolactin (PRL) levels acting at the central nervous system. The present experiments were designed to evaluate whether the gamma-aminobutyric acid B agonist was also effective in inhibit... |
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Differential effects of phosphonic analogues of GABA on GABA(B) autoreceptors in rat neocortical slices.
Naunyn Schmiedebergs Arch. Pharmacol. 357 , 408-412, (1998) The effects of five phosphonic derivatives of GABA on the release of [3H]-GABA from rat neocortical slices, preloaded with [3H]-GABA, were investigated. Phaclofen and 4-aminobutylphosphonic acid (4-ABPA) increased the overflow of [3H] evoked by electrical sti... |
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Evidence for pharmacologically distinct subsets of GABAB receptors.
Brain Res. Bull. 21 , 439-443, (1988) Activation of GABAB receptors augments neurotransmitter-stimulated cyclic AMP accumulation while inhibiting forskolin-mediated second messenger production. Previous studies have revealed that GABAB receptors are associated with a pertussis toxin sensitive G p... |
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Pharmacology of the GABAB receptor in amphibian retina.
Brain Res. 660 , 267-274, (1994) Amacrine and ganglion cells in the amphibian retina contain GABAB, as well as GABAA, receptors. Baclofen, a GABAB agonist, hyperpolarizes the dark membrane potential of these third order neurons and makes their light responses more transient. GABAB receptors ... |
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Structural determinants of activity at the GABAB receptor. A comparison of phosphoethanolamine and related GABA analogs.
Mol. Chem. Neuropathol. 26(1) , 15-30, (1995) Phosphoethanolamine is a phosphomonoester that is reduced in Alzheimer disease brain. Despite its close structural similarity to GABA and the GABAB partial agonist 3-aminopropylphosphonic acid, phosphoethanolamine binds very poorly to GABAB receptors (IC50 = ... |
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Distal and deglutitive inhibition in the rat esophagus: role of inhibitory neurotransmission in the nucleus tractus solitarii.
Gastroenterology 118(2) , 328-36, (2000) This study aimed to show the presence of deglutitive and distal inhibition in the rat esophagus and to differentiate the underlying neural mechanisms.Under urethane anesthesia, the pharyngoesophageal tract was fitted with water-filled balloons for luminal dis... |
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Replacement of ethanolamine phosphate by 3-aminopropylphosphonate in the phospholipids of Tetrahymena.
Arch. Biochem. Biophys. 206(2) , 420-3, (1981)
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Synthesis and characterization of functionalized magnetic maghemite nanoparticles with fluorescent probe capabilities for biological applications.
J. Biomed. Mater. Res. B. Appl. Biomater. 92(2) , 353-60, (2010) Nanoparticles with innovative optical, chemical, and magnetic properties combined in a single nanoparticle may be useful as biosensors, targeting agents, and therapeutic agents in the biomedical field. This study describes new magnetic nanoparticles (MNPs) co... |
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New magnetic resonance imaging contrast agents for infarct imaging based on phosphonate derivatives of Gd-DTPA.
Invest. Radiol. 26 Suppl 1 , S242-4; discussion S245-7, (1991)
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Phosphatidylcholine homeostasis in phosphatidylethanolamine-depleted Tetrahymena.
Arch. Biochem. Biophys. 246(1) , 347-54, (1986) The relative contributions of the two pathways of phosphatidylcholine biosynthesis, phosphatidylethanolamine N-methyltransferase (EC 2.1.1.17) and diacylglycerol: CDP-choline cholinephosphotransferase (EC 2.7.8.1), are altered in the ciliate protozoan Tetrahy... |