对甲氧基肉桂酸异辛酯
对甲氧基肉桂酸异辛酯结构式
|
常用名 | 对甲氧基肉桂酸异辛酯 | 英文名 | 2-Ethylhexyl trans-4-methoxycinnamate |
|---|---|---|---|---|
| CAS号 | 83834-59-7 | 分子量 | 290.397 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 405.3±20.0 °C at 760 mmHg | |
| 分子式 | C18H26O3 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 171.6±16.4 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
J. Sci. Ind. Res. 65(10) , 808, (2006) Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be tra... |
|
|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Chem. Res. Toxicol. 23 , 1215-22, (2010) Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification o... |
|
|
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Drug Metab. Dispos. 38 , 2302-8, (2010) Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predictive in vivo, in vitro, and in silico models to identify comp... |
|
|
Fast determination of octinoxate and oxybenzone uv filters in swimming pool waters by gas chromatography/mass spectrometry after solid-phase microextraction.
J. Sep. Sci. 38 , 2286-97, (2015) A fast gas chromatography/mass spectrometry method was developed and validated for the analysis of the potential endocrine disrupters octinoxate and oxybenzone in swimming pool water samples based on the solvent-free solid-phase microextraction technique. The... |
|
|
Co-occurrence of musk fragrances and UV-filters in seafood and macroalgae collected in European hotspots.
Environ. Res. 143 , 65-71, (2015) In the last decades, awareness regarding personal care products (PCP), i.e. synthetic organic chemicals frequently used in cosmetic and hygienic products, has become a forward-looking issue, due to their persistency in the environment and their potential mult... |
|
|
Occurrence, distribution and ecological risk assessment of multiple classes of UV filters in marine sediments in Hong Kong and Japan.
J. Hazard. Mater. 292 , 180-7, (2015) Organic ultraviolet (UV) filters are used widely in various personal care products and their ubiquitous occurrence in the aquatic environment has been reported in recent years. However, data on their fate and potential impacts in marine sediments is limited. ... |
|
|
Preparation and evaluation of novel octylmethoxycinnamate-loaded solid lipid nanoparticles.
Int. J. Cosmet. Sci. 37 , 446-53, (2015) Octylmethoxycinnamate (OMC)-loaded solid lipid nanoparticles (SLNs) were prepared by ultrasonic emulsification method. Effects of process variables and formulation composition were investigated on particle size and polydispersity index (PI), and the UV absorb... |
|
|
Wogonoside induces apoptosis in Bel-7402, a hepatocellular carcinoma cell line, by regulating Bax/Bcl-2.
Nanoscale 7 , 13075-87, (2015) The anticancer effect of Scutellaria baicalensis extract has recently become a topic of interest. In this study, the anticancer effects and underlying mechanisms of wogonoside, the main constituent of Scutellaria baicalensis, were investigated in a human hepa... |
|
|
Supervised exercise, stent revascularization, or medical therapy for claudication due to aortoiliac peripheral artery disease: the CLEVER study.
J. Am. Coll. Cardiol. 65(10) , 999-1009, (2015) Treatment for claudication that is due to aortoiliac peripheral artery disease (PAD) often relies on stent revascularization (ST). However, supervised exercise (SE) is known to provide comparable short-term (6-month) improvements in functional status and qual... |