2-硝基丙烷
一般危化品
2-硝基丙烷结构式
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常用名 | 2-硝基丙烷 | 英文名 | 2-Nitropropane |
|---|---|---|---|---|
| CAS号 | 79-46-9 | 分子量 | 89.093 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 121.2±8.0 °C at 760 mmHg | |
| 分子式 | C3H7NO2 | 熔点 | -93 °C | |
| MSDS | 中文版 美版 | 闪点 | 37.2±0.0 °C | |
| 符号 |
GHS02, GHS06, GHS08 |
信号词 | Danger |
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Affinity chromatographic selection of carbonylated proteins followed by identification of oxidation sites using tandem mass spectrometry.
Anal. Chem. 77(8) , 2386-92, (2005) It has been shown that oxidatively modified forms of proteins accumulate during oxidative stress, aging, and in some age-related diseases. One of the unique features of a wide variety of routes by which proteins are oxidized is the generation of carbonyl grou... |
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Formaldehyde-releasers in cosmetics: relationship to formaldehyde contact allergy. Part 2. Patch test relationship to formaldehyde contact allergy, experimental provocation tests, amount of formaldehyde released, and assessment of risk to consumers allergic to formaldehyde.
Contact Dermatitis 62(1) , 18-31, (2010) This is the second part of an article on formaldehyde-releasers in cosmetics. The patch test relationship between the releasers in cosmetics to formaldehyde contact allergy is reviewed and it is assessed whether products preserved with formaldehyde-releasers ... |
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Evaluation of carcinogenic responses in the Eker rat following short-term exposure to selected nephrotoxins and carcinogens.
Toxicol. Pathol. 30(5) , 559-64, (2002) This study examined the response of the Eker rat to nephrotoxic compounds and to genotoxic nonrenal carcinogens. Groups of male Eker rats received either no treatment; a vehicle treatment; treatment with a noncarcinogenic nephrotoxin (aluminum nitrilotriaceta... |
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Ultraviolet photodissociation dynamics of the n-propyl and i-propyl radicals.
J. Chem. Phys. 142 , 224306, (2015) Ultraviolet (UV) photodissociation dynamics of jet-cooled n-propyl (n-C3H7) radical via the 3s Rydberg state and i-propyl (i-C3H7) radical via the 3p Rydberg states are studied in the photolysis wavelength region of 230-260 nm using high-n Rydberg atom time-o... |
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Age-related loss of the DNA repair response following exposure to oxidative stress.
J. Gerontol. A. Biol. Sci. Med. Sci. 61(5) , 427-34, (2006) Young (4- to 6-month-old) and aged (24- to 28-month-old) mice were exposed to 2-nitropropane (2-NP), a DNA oxidizing agent, and the ability to induce DNA polymerase beta (beta-pol) and AP endonuclease (APE) was determined. In contrast to the inducibility of t... |
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Reversal of enantioselectivity by tuning the conformational flexibility of phase-transfer catalysts.
Angew. Chem. Int. Ed. Engl. 49(15) , 2772-6, (2010)
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Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice.
Free Radic. Biol. Med. 46(11) , 1488-99, (2009) Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is the redox regulator of multiple stress-inducible transcription factors, such as NF-kappaB, and the major 5'-endonuclease in base excision repair (BER). We utilized mice containing a heterozyg... |
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Crystal structure of 2-nitropropane dioxygenase complexed with FMN and substrate. Identification of the catalytic base.
J. Biol. Chem. 281(27) , 18660-7, (2006) Nitroalkane compounds are widely used in chemical industry and are also produced by microorganisms and plants. Some nitroalkanes have been demonstrated to be carcinogenic, and enzymatic oxidation of nitroalkanes is of considerable interest. 2-Nitropropane dio... |
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Mutagenicity of N-nitrosodiethanolamine in a V79-derived cell line expressing two human biotransformation enzymes.
Mutat. Res. 643(1-2) , 64-9, (2008) N-nitrosodiethanolamine (NDELA) has demonstrated carcinogenic activity in various rodent models. However, it is negative or only weakly active in standard in vitro genotoxicity assays. This poor response might be due to the requirement of specific enzymes for... |
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Involvement of a flavosemiquinone in the enzymatic oxidation of nitroalkanes catalyzed by 2-nitropropane dioxygenase.
J. Biol. Chem. 280(7) , 5195-204, (2005) 2-Nitropropane dioxygenase (EC 1.13.11.32) catalyzes the oxidation of nitroalkanes into their corresponding carbonyl compounds and nitrite. In this study, the ncd-2 gene encoding for the enzyme in Neurospora crassa was cloned, expressed in Escherichia coli, a... |