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二碳酸二叔丁酯

二碳酸二叔丁酯结构式
二碳酸二叔丁酯结构式
品牌特惠专场
常用名 二碳酸二叔丁酯 英文名 Di-tert-butyl dicarbonate
CAS号 24424-99-5 分子量 218.247
密度 0.949 沸点 56-57 ºC (0.5 torr)
分子式 C10H18O5 熔点 23 °C(lit.)
MSDS 中文版 美版 闪点 37 ºC
符号 GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
信号词 Danger

Sialidases as regulators of bioengineered cellular surfaces.

Glycobiology 25 , 784-91, (2015)

Human sialidases (NEUs) catalyze the removal of N-acetyl neuraminic acids from the glycome of the cell and regulate a diverse repertoire of nominal cellular functions, such as cell signaling and adhesion. A greater understanding of their substrate permissivit...

Mixed alkyl aryl phosphonate esters as quenched fluorescent activity-based probes for serine proteases.

Org. Biomol. Chem. 13(8) , 2293-9, (2015)

Activity-based probes (ABPs) are powerful tools for the analysis of active enzyme species in whole proteomes, cells or animals. Quenched fluorescent ABPs (qABPs) can be applied for real time imaging, allowing the visualization of dynamic enzyme activation by ...

Regioselective chemical and rapid enzymatic synthesis of a novel redox – Antiproliferative molecular hybrid.

Eur. J. Med. Chem. 96 , 47-57, (2015)

Recent science evidenced the interlinkage of oxidative stress and cancer. Due to the inherent complexity of cancer and its accompanying effect of oxidative stress, novel molecules, containing combinatorial functionalities should be targeted. Herein, we synthe...

In vivo imaging of reactive oxygen species in mouse brain by using [3H]hydromethidine as a potential radical trapping radiotracer.

J. Cereb. Blood Flow Metab. 34(12) , 1907-13, (2014)

To assess reactive oxygen species (ROS) production by detecting the fluorescent oxidation product, hydroethidine has been used extensively. The present study was undertaken to evaluate the potential of the hydroethidine derivative as a radiotracer to measure ...

Comparison of two self-assembled macromolecular prodrug micelles with different conjugate positions of SN38 for enhancing antitumor activity.

Int. J. Nanomedicine 10 , 2295-311, (2015)

7-Ethyl-10-hydroxycamptothecin (SN38), an active metabolite of irinotecan (CPT-11), is a remarkably potent antitumor agent. The clinical application of SN38 has been extremely restricted by its insolubility in water. In this study, we successfully synthesized...

Effect of Relative Arrangement of Cationic and Lipophilic Moieties on Hemolytic and Antibacterial Activities of PEGylated Polyacrylates.

Int. J. Mol. Sci. 16 , 23867-80, (2015)

Synthetic amphiphilic polymers have been established as potentially efficient agents to combat widespread deadly infections involving antibiotic resistant superbugs. Incorporation of poly(ethylene glycol) (PEG) side chains into amphiphilic copolymers can redu...

Three-Layered Biodegradable Micelles Prepared by Two-Step Self-Assembly of PLA-PEI-PLA and PLA-PEG-PLA Triblock Copolymers as Efficient Gene Delivery System.

Macromol. Biosci. 15 , 698-711, (2015)

"Three-layered micelles" (3LM) composed of two triblock copolymers, poly(L-lactide)-b-polyethyleneimine-b-poly(L-lactide) (PLLA-PEI-PLLA) and poly(L-lactide)-b-poly(ethylene glycol)-b-poly(L-lactide) (PLLA-PEG-PLLA) are designed to combine electrostatic inter...

Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate.

Nat. Commun. 6 , 6715, (2015)

The widespread emergence of Plasmodium falciparum (Pf) strains resistant to frontline agents has fuelled the search for fast-acting agents with novel mechanism of action. Here, we report the discovery and optimization of novel antimalarial compounds, the tria...

Cyclometalated iridium(III) bipyridyl-phenylenediamine complexes with multicolor phosphorescence: synthesis, electrochemistry, photophysics, and intracellular nitric oxide sensing.

ChemMedChem 9(6) , 1316-29, (2014)

We present a new class of phosphorescent cyclometalated iridium(III) bipyridyl-phenylenediamine complexes [Ir(N^C)2 (bpy-DA)](PF6 ) (bpy-DA=4-(N-(2-amino-5-methoxyphenyl)aminomethyl)-4'-methyl-2,2'-bipyridine; HN^C=2-(2,4-difluorophenyl)pyridine (Hdfppy) (1 a...

Surface plasmon resonance based on molecularly imprinted nanoparticles for the picomolar detection of the iron regulating hormone Hepcidin-25.

J. Nanobiotechnology 13 , 51, (2015)

Molecularly imprinted polymer (MIP) technique is a powerful mean to produce tailor made synthetic recognition sites. Here precipitation polymerization was exploited to produce a library of MIP nanoparticles (NPs) targeting the N terminus of the hormone Hepcid...