胸腺五肽
胸腺五肽结构式
|
常用名 | 胸腺五肽 | 英文名 | Thymopentin |
|---|---|---|---|---|
| CAS号 | 69558-55-0 | 分子量 | 679.765 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C30H49N9O9 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
|
Stability and aerosolization of pressurized metered dose inhalers containing thymopentin nanoparticles produced using a bottom-up process.
Int. J. Pharm. 427(2) , 385-92, (2012) The objective of this study was to investigate the stability and aerosolization of pressurized metered dose inhalers (pMDIs) containing thymopentin nanoparticles. Thymopentin nanoparticles, fabricated by a bottom-up process, were suspended in hydrofluoroalkan... |
|
|
Separation and purification of thymopentin with molecular imprinting membrane by solid phase extraction disks.
J. Pharm. Biomed. Anal. 102 , 137-43, (2014) The synthesis and performance of molecularly imprinted membranes (MIMs) as a solid phase extraction packing materials for the separation and purification of thymopentin from crude samples was described. In order to increase structural selectivity and imprinti... |
|
|
[Vulvar lesions caused by Papillomavirus (HPV): effectiveness of thymopentin (Syntomoduline). First results and experiences].
Minerva Ginecol. 43(1-2) , 53-6, (1991) The study included two different sized groups of patients suffering from various degrees of valvular microcondylomatosis. A group of 40 patients was treated using combined therapy while a second group of 20 patients received immunomodulating therapy alone wit... |
|
|
Peptides and polypeptides as modulators of the immune response: thymopentin--an example with unknown mode of action.
Pharm. Acta Helv. 73(6) , 265-73, (1999) Peptides and polypeptides play a critical role in the immune system and are therefore predestined as a source for new approaches in immunotherapy. For example, antigenic peptides which can trigger a specific immunological response have been successfully used ... |
|
|
Immunomodulation with thymopentin: in vitro studies.
Med. Oncol. Tumor Pharmacother. 6(1) , 19-23, (1989) Immunomodulation is interpreted as a temporary alert in a certain part of the immune system. The activation of immune competent cells is presented as a possible basic mechanism of this phenomenon. In the absence of a primary stimulus, immunomodulation remains... |
|
|
Thymopoietin to thymopentin: experimental studies.
Surv. Immunol. Res. 4 Suppl 1 , 1-10, (1985) Thymopoietin is a polypeptide hormone of the thymus consisting of 49 amino acids. The pentapeptide thymopentin (TP-5) Arg-Lys-Asp-Val-Tyr, corresponding to amino acids 32-36 of thymopoietin, appears to represent the active site of thymopoietin in that it has ... |
|
|
Inhalable microparticles as carriers for pulmonary delivery of thymopentin-loaded solid lipid nanoparticles.
Pharm. Res. 27(9) , 1977-86, (2010) Microparticles containing solid lipid nanoparticles (SLNs) are receiving increased attention as carriers for the lung delivery of the SLNs. Thus, we aim to prepare the hybrid microparticles and thoroughly evaluate their feasibility for the pulmonary drug deli... |
|
|
Thymic peptides for treatment of cancer patients.
Cochrane Database Syst. Rev. (2) , CD003993, (2011) Purified thymus extracts (pTE) and synthetic thymic peptides (sTP) are thought to enhance the immune system of cancer patients in order to fight the growth of tumour cells and to resist infections due to immunosuppression induced by the disease and antineopla... |
|
|
Repeated transfusions of autologous cytokine-induced killer cells for treatment of haematological malignancies in elderly patients: a pilot clinical trial.
Hematol. Oncol. 30(3) , 115-22, (2012) The elderly population is susceptible to haematological malignancies, and these elderly patients are intolerant to cytotoxic drugs. Therefore, the exploration of a safe and reliable strategy exclusive of chemotherapy is critical in improving the prognosis of ... |
|
|
Thymopentin treatment of rheumatoid arthritis.
Arzneimittelforschung 44(10) , 1145-9, (1994) Although the etiology of rheumatoid arthritis (RA) is unknown, there is solid evidence that immunological factors play a pivotal role in its pathogenesis. It seems that a hyporeactivity of local (intraarticular) T-suppressor cells would permit an excessive im... |