环庚三烯酮
环庚三烯酮结构式
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常用名 | 环庚三烯酮 | 英文名 | TROPONE |
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| CAS号 | 539-80-0 | 分子量 | 106.12200 | |
| 密度 | 1.094 | 沸点 | 113ºC (15 torr) | |
| 分子式 | C7H6O | 熔点 | -7ºC | |
| MSDS | 中文版 美版 | 闪点 | 85.6ºC |
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Benzo[cd]azulene skeleton: azulene, heptafulvene, and tropone derivatives.
Org. Lett. 11(23) , 5363-5, (2009) Due to our interest in protein kinase modulating compounds, we developed syntheses for benzo[cd]azulenes. By using very common catalysts and reagents, such as t-BuOK, HCl, and mCPBA, the commercially available guaiazulene is converted in three steps into tric... |
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Tropylium tetrafluoroborate, a novel substrate for aldehyde oxidase.
Biochem. Biophys. Res. Commun. 140(2) , 609-15, (1986) The stabilized carbonium ion salt, tropylium tetrafluoroborate, was oxidized to tropone (cycloheptatrienone) by rabbit liver aldehyde oxidase but not by the closely related molybdenum hydroxylase, xanthine oxidase. The tropylium cation is an aromatic hydrocar... |
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Potential of Piperazinylalkylester Prodrugs of 6-Methoxy-2-Naphthylacetic Acid (6-MNA) for Percutaneous Drug Delivery.
Z. Naturforsch., C, J. Biosci. 59(3-4) , 184-6, (2004) Piperazinylalkyl ester prodrugs (4a-5d) of 6-methoxy-2-naphthylacetic acid (6-MNA) (1) were synthesized and evaluated in vitro for the purpose of percutaneous drug delivery. These ionizable prodrugs exhibited varying aqueous solubilities and lipophilicities d... |
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Pernambucone, a new tropone derivative from Croton argyroglossum.
Pharmazie 64(5) , 350-1, (2009) Two tropone derivatives, orobanone (1), previously isolated from Orobanche rapum-genistae, and the new natural product pernambucone (3,8-dimethyl-5-isopropyl-2,3-dihydro-1H-azulene-1,6-dione, 2), were isolated from the sterm bark of Croton argyroglossum. The ... |
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Metal-catalyzed [6 + 3] cycloaddition of tropone with azomethine ylides: a practical access to piperidine-fused bicyclic heterocycles.
J. Am. Chem. Soc. 136(6) , 2625-9, (2014) The first metal-catalyzed [6 + 3] cycloaddition of tropone with azomethine ylides has been developed. With the use of a chiral ferrocenylphosphine-copper(I) complex as the catalyst, the asymmetric variant of the [6 + 3] cycloaddition has also been successfull... |
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An N-heterocyclic carbene-catalyzed [8 + 3] annulation of tropone and enals via homoenolate.
J. Org. Chem. 71(23) , 8964-5, (2006) A novel protocol for the annulation of tropone to enals involving nucleophilic heterocyclic carbene (NHC) catalyzed homoenolate formation has been developed. Interestingly, the reaction led to bicyclic delta-lactones instead of the expected gamma-spirolactone... |
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Application of Lewis acid catalyzed tropone [6+4] cycloadditions to the synthesis of the core of CP-225,917.
Org. Lett. 3(26) , 4189-92, (2001) The carbocyclic core of CP-225,917 and CP-263,114 is accessible through the [6+4] cycloaddition of a tropone with a 2-substituted cyclopentadiene. Examination of this reaction has revealed for the first time that this cycloaddition process is catalyzed by Lew... |
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Access to a welwitindolinone core using sequential cycloadditions.
Org. Lett. 11(16) , 3782-5, (2009) A concise approach to the core skeleton of the welwitindolinone alkaloids was developed on the basis of sequential cycloaddition reactions. First, a palladium catalyzed enantioselective [6 + 3] trimethylenemethane cycloaddition onto a tropone nucleus was used... |
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Asymmetric synthesis of bicyclo[4.3.1]decadienes and bicyclo[3.3.2]decadienes via [6 + 3] trimethylenemethane cycloaddition with tropones.
J. Am. Chem. Soc. 130(45) , 14960-1, (2008) The cyanosubstituted trimethylenemethane donor undergoes palladium-catalyzed [6 + 3] cycloaddition with a variety of tropones to yield bicyclo[4.3.1]decadienes in excellent regio-, diastereo-, and enantioselectivity. Products of the Pd-TMM [6 + 3] cycloadditi... |
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Structural, electronic and magnetic properties of Cu(II) complexes of 2-substituted tropones bearing a ferrocenyl group at 5-position.
Dalton Trans. 39(9) , 2293-300, (2010) Heterotrinuclear Fe(II)-Cu(II)-Fe(II) complexes [Cu(FcTropOMe)(2)(H(2)O)(2)](OTf)(2) (FcTropOMe = 5-ferrocenyl-2-methoxytropone) (1), [Cu(FcTropNEt(2))(2)](OTf)(2) (FcTropNEt(2) = 2-(N,N-diethylamino)-5-ferrocenyltropone) (2) and [Cu(FcTropNEt)(2)] (FcTropNEt... |