环丙甲酸
环丙甲酸结构式
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常用名 | 环丙甲酸 | 英文名 | Cyclopropanecarboxylic acid |
|---|---|---|---|---|
| CAS号 | 1759-53-1 | 分子量 | 86.09 | |
| 密度 | 1.085 | 沸点 | 182-184 ºC | |
| 分子式 | C4H6O2 | 熔点 | 17-19 ºC | |
| MSDS | 中文版 美版 | 闪点 | 71 ºC | |
| 符号 |
GHS05 |
信号词 | Danger |
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Presynaptic GABAB autoreceptor regulation of nicotinic acetylcholine receptor mediated [(3)H]-GABA release from mouse synaptosomes.
Biochem. Pharmacol. 91(1) , 87-96, (2014) Activation of nicotinic acetylcholine receptors (nAChRs) can elicit neurotransmitter release from presynaptic nerve terminals. Mechanisms contributing to cell-and-terminal specific regulation of nAChR-mediated neurotransmitter exocytosis are not fully underst... |
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De novo expression of parvalbumin in ependymal cells in response to brain injury promotes ependymal remodeling and wound repair.
Glia 63(4) , 567-94, (2015) The calcium-binding protein parvalbumin (PV) hallmarks subpopulations of interneurons in the murine brain. We serendipitously observed the de novo expression of PV in ependymal cells of the lateral ventricle wall following in vivo lesioning and brain slicing ... |
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Metabolism and Disposition of Cabozantinib in Healthy Male Volunteers and Pharmacologic Characterization of Its Major Metabolites.
Drug Metab. Dispos. 43 , 1190-207, (2015) Metabolism and excretion of cabozantinib, an oral inhibitor of receptor tyrosine kinases, was studied in 8 healthy male volunteers after a single oral dose of 175 mg cabozantinib l-malate containing (14)C-cabozantinib (100 µCi/subject). Total mean radioactivi... |
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Pd(II)-catalyzed enantioselective C-H activation of cyclopropanes.
J. Am. Chem. Soc. 49th ed., 133 , 19598-19601, (2011) Systematic ligand development has led to the identification of novel mono-N-protected amino acid ligands for Pd(II)-catalyzed enantioselective C-H activation of cyclopropanes. A diverse range of organoboron reagents can be used as coupling partners, and the r... |
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A new sigma ligand, (+/-)-PPCC, antagonizes kappa opioid receptor-mediated antinociceptive effect.
Life Sci. 82(11-12) , 549-53, (2008) The compound (1R,2S/1S,2R)-2-[4-hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl) cyclopropanecarboxylate [(+/-)-PPCC] is a ligand with high affinity for sigma (sigma) sites of which the selectivity towards several other receptor systems has been demo... |
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Comparison of in vitro carnitine and glycine conjugation with branched-side chain and cyclic side chain carboxylic acids in rats.
Drug Metab. Dispos. 25(2) , 149-53, (1997) The substrate specificity for carnitine conjugation was examined using rat hepatocytes and kidney slices and compared with glycine conjugation which is a competitive pathway through the CoA thioester. For both hepatocytes and kidney slices, the best substrate... |
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The effects of cyclopropane carboxylic acid on hepatic pyruvate metabolism.
Metab. Clin. Exp. 32(7) , 736-44, (1983) The effects of the hypoglycemic agent, cyclopropane carboxylate, on the metabolism of various substrates that enter the mitochondrion via the mitochondrial monocarboxylate transporter were investigated in perfused rat livers. Metabolism of pyruvate, branched-... |
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Novel pathway for utilization of cyclopropanecarboxylate by Rhodococcus rhodochrous.
Appl. Environ. Microbiol. 70(1) , 224-8, (2004) A new strain isolated from soil utilizes cyclopropanecarboxylate as the sole source of carbon and energy and was identified as Rhodococcus rhodochrous (H. Nishihara, Y. Ochi, H. Nakano, M. Ando, and T. Toraya, J. Ferment. Bioeng. 80:400-402, 1995). A novel pa... |
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Potential energy scans and vibrational assignments of cyclopropanecarboxylic acid and cyclopropanecarboxamide.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 71(4) , 1540-6, (2008) The structural stability and internal rotations in cyclopropanecarboxylic acid and cyclopropanecarboxamide were investigated by the DFT-B3LYP and the ab initio MP2 calculations using 6-311G** and 6-311+G** basis sets. The computations were extended to the MP4... |
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Modulation of NMDA-induced cytosolic calcium levels by ACPC in cultured cerebellar granule cells.
Neuroreport 7(11) , 1824-8, (1996) The effect of 1-aminocyclopropanecarboxylic acid (ACPC) on the potentiation by glycine of N-methyl-D-aspartate (NMDA)-evoked increases in intracellular free calcium concentration [Ca2+]i was examined in cultured rat cerebellar granule cells. NMDA (50 microM) ... |