S-(2-羟基-5-硝基苄基)-6-硫代肌苷结构式
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常用名 | S-(2-羟基-5-硝基苄基)-6-硫代肌苷 | 英文名 | S-(2-HYDROXY-5-NITROBENZYL)-6-THIOINOSINE |
|---|---|---|---|---|
| CAS号 | 56964-73-9 | 分子量 | 435.41100 | |
| 密度 | 1.87g/cm3 | 沸点 | 829.7ºC at 760mmHg | |
| 分子式 | C17H17N5O7S | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 455.6ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity.
Bioorg. Med. Chem. 16 , 3848-65, (2008) Conformationally constrained analogue synthesis was undertaken to aid in pharmacophore mapping and 3D-QSAR analysis of nitrobenzylmercaptopurine riboside (NBMPR) congeners as equilibriative nucleoside transporter 1 (ENT1) inhibitors. In our previous study [J.... |
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Inhibitors of nucleoside transport. A structure-activity study using human erythrocytes.
J. Med. Chem. 18 , 968, (1975) The passage of nucleosides across the plasma membrane of erythrocytes is a membrane-mediated process which is strongly inhibited by derivatives of 9-beta-D-ribofuranosylpurine (1) with S, O, or N atoms at the purine 6 position bearing variously substituted ar... |
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