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S-(2-羟基-5-硝基苄基)-6-硫代肌苷

S-(2-羟基-5-硝基苄基)-6-硫代肌苷结构式
S-(2-羟基-5-硝基苄基)-6-硫代肌苷结构式
品牌特惠专场
常用名 S-(2-羟基-5-硝基苄基)-6-硫代肌苷 英文名 S-(2-HYDROXY-5-NITROBENZYL)-6-THIOINOSINE
CAS号 56964-73-9 分子量 435.41100
密度 1.87g/cm3 沸点 829.7ºC at 760mmHg
分子式 C17H17N5O7S 熔点 N/A
MSDS 中文版 美版 闪点 455.6ºC
符号 GHS07
GHS07
信号词 Warning

Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity.

Bioorg. Med. Chem. 16 , 3848-65, (2008)

Conformationally constrained analogue synthesis was undertaken to aid in pharmacophore mapping and 3D-QSAR analysis of nitrobenzylmercaptopurine riboside (NBMPR) congeners as equilibriative nucleoside transporter 1 (ENT1) inhibitors. In our previous study [J....

Inhibitors of nucleoside transport. A structure-activity study using human erythrocytes.

J. Med. Chem. 18 , 968, (1975)

The passage of nucleosides across the plasma membrane of erythrocytes is a membrane-mediated process which is strongly inhibited by derivatives of 9-beta-D-ribofuranosylpurine (1) with S, O, or N atoms at the purine 6 position bearing variously substituted ar...