1-氨基蒽
1-氨基蒽结构式
|
常用名 | 1-氨基蒽 | 英文名 | 1-Anthracenamine |
|---|---|---|---|---|
| CAS号 | 610-49-1 | 分子量 | 193.24400 | |
| 密度 | 1.208g/cm3 | 沸点 | 408.2ºC at 760 mmHg | |
| 分子式 | C14H11N | 熔点 | 114-118 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 224.4ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Antitumor activity of acriflavine in lung adenocarcinoma cell line A549.
Anticancer Res. 34(11) , 6467-72, (2014) Aim/Materials and Methods: In order to develop better drugs against non-small cell lung cancer (NSCLC), we screened a variety of compounds and treated the human lung adenocarcinoma cell line A549 with different drug concentrations. We then examined the cell v... |
|
|
Stereoselectivity of isoflurane in adhesion molecule leukocyte function-associated antigen-1.
PLoS ONE 9(5) , e96649, (2014) Isoflurane in clinical use is a racemate of S- and R-isoflurane. Previous studies have demonstrated that the effects of S-isoflurane on relevant anesthetic targets might be modestly stronger (less than 2-fold) than R-isoflurane. The X-ray crystallographic str... |
|
|
Biopartitioning micellar chromatography to predict mutagenicity of aromatic amines.
Eur. J. Med. Chem. 42 , 1396-402, (2007) Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry and their mutagenic capacity. Biopartitioning micellar chr... |
|
|
A high-throughput approach for identification of novel general anesthetics.
PLoS ONE 4(9) , e7150, (2009) Anesthetic development has been a largely empirical process. Recently, we described a GABAergic mimetic model system for anesthetic binding, based on apoferritin and an environment-sensitive fluorescent probe. Here, a competition assay based on 1-aminoanthrac... |
|
|
Phenylalanine 35 and tyrosine 82 are involved in the uptake and release of ligand by porcine odorant-binding protein.
Biochim. Biophys. Acta 1794(8) , 1142-50, (2009) Structural and molecular dynamics studies have pointed out the role of aromatic residues in the uptake of ligand by porcine odorant-binding protein (pOBP). The shift of Tyr82 from its position during the opening of the binding cavity has been shown, and was s... |
|
|
In vitro lipolysis by human pancreatic lipase is specifically abolished by its inactive forms.
Biochim. Biophys. Acta 1645(2) , 241-6, (2003) In human adults, the enzymatic hydrolysis of dietary fat along the digestive tract is sequentially catalyzed by two main enzymes, human gastric lipase (HGL) and human pancreatic lipase (HPL). Both a chemically inhibited form of HPL as well as an inactive HPL ... |
|
|
Properties of mouse vomeronasal receptor and assessment of its role in pheromone signalling.
Rapid Commun. Mass Spectrom. 25(2) , 262-70, (2011) Vomeronasal type 2 receptor (V2Rx) from Swiss mouse (Mus musculus (L.)) was analyzed by high-resolution ion-exchange chromatography, reversed-phase high-performance liquid chromatography (RP-HPLC), matrix-assisted laser desorption/ionization time-of-flight ma... |
|
|
Effect of 1-aminoanthracene (1-AMA) binding on the structure of three lipocalin proteins, the dimeric β lactoglobulin, the dimeric odorant binding protein and the monomeric α1-acid glycoprotein. Fluorescence spectra and lifetimes studies.
J. Fluoresc. 20(5) , 973-83, (2010) We studied effect of 1-aminoanthracene (1-AMA) binding on the structures of dimeric β lactoglobulin, dimeric odorant binding protein (OBP) and monomeric α(1)-acid glycoprotein (lipocalin family proteins) by monitoring fluorescence excitation spectra and measu... |
|
|
Characterization of the oligomerization and ligand-binding properties of recombinant rat lipocalin 11.
Biochim. Biophys. Acta 1834(1) , 1-7, (2013) Lipocalin 11 (Lcn11), a recently identified member of the lipocalin family, potentially plays crucial physiological roles in male reproduction. In this present work, we cloned, expressed and purified the rat Lcn11 (rLcn11) protein Escherichia coli. A C59A/C15... |
|
|
Odorant binding initially occurring at the central pocket in bovine odorant-binding protein.
Biochem. Biophys. Res. Commun. 333(4) , 1227-33, (2005) Why bovine odorant-binding protein (OBPb), among OBP family, assumes a dimeric structure has been unclear. Here we clarified, by measuring the fluorescence of intrinsic tryptophan and tyrosine residues of intact OBPb and OBPb whose C-terminal 10 amino acids w... |