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β-氰基-L-丙氨酸

β-氰基-L-丙氨酸结构式
β-氰基-L-丙氨酸结构式
品牌特惠专场
常用名 β-氰基-L-丙氨酸 英文名 3-cyano-L-alanine
CAS号 6232-19-5 分子量 114.103
密度 1.3±0.1 g/cm3 沸点 368.1±32.0 °C at 760 mmHg
分子式 C4H6N2O2 熔点 N/A
MSDS 美版 闪点 176.4±25.1 °C

Evolution of heteromeric nitrilase complexes in Poaceae with new functions in nitrile metabolism.

Proc. Natl. Acad. Sci. U. S. A. 104(47) , 18848-53, (2007)

Members of the nitrilase 4 (NIT4) family of higher plants catalyze the conversion of beta-cyanoalanine to aspartic acid and asparagine, a key step in cyanide detoxification. Grasses (Poaceae) possess two different NIT4 homologs (NIT4A and NIT4B), but none of ...

Vicianin, prunasin, and beta-cyanoalanine in common vetch seed as sources of urinary thiocyanate in the rat.

J. Agric. Food Chem. 49(10) , 5075-80, (2001)

When young rats were fed a diet containing common vetch seed for 1 month, they excreted in the urine approximately 7 times more thiocyanate than they had ingested. Vicianin, prunasin, and beta-cyanoalanine were identified as principal dietary sources of the e...

Maize nitrilases have a dual role in auxin homeostasis and beta-cyanoalanine hydrolysis.

J. Exp. Bot. 58(15-16) , 4225-33, (2007)

The auxin indole-3-acetic acid (IAA), which is essential for plant growth and development, is suggested to be synthesized via several redundant pathways. In maize (Zea mays), the nitrilase ZmNIT2 is expressed in auxin-synthesizing tissues and efficiently hydr...

The β-cyanoalanine pathway is involved in the response to water deficit in Arabidopsis thaliana.

Plant Physiol. Biochem. 63 , 159-69, (2013)

The β-cyanoalanine pathway is primarily responsible for detoxification of excess cyanide produced by plants. Recent evidence suggests that cyanide detoxification via this pathway may be involved in the response and tolerance to water deficit in plants. The ai...

Clinical utility of grading criteria for submucosal invasion in the prognosis of T1 colorectal carcinomas.

J. Gastroenterol. 38(1) , 37-44, (2003)

The clinical utility of relative and absolute grading criteria for submucosal invasion in T1 colorectal carcinomas has been controversial.In 51 T1 colorectal carcinomas, depth of submucosal invasion was graded either according to a modified Haggitt's classifi...

Modulation of cyanoalanine synthase and O-acetylserine (thiol) lyases A and B activity by beta-substituted alanyl and anion inhibitors.

J. Exp. Bot. 53(368) , 439-45, (2002)

The reaction mechanisms of three enzymes belonging to a single gene family are compared: a cyanoalanine synthase and two isoforms of O-acetylserine (thiol) lyase (O-ASTL) isolated from spinach (Spinacea oleracea L. cv. Medina). O-ASTL represents a major regul...

13C-NMR studies on the reaction intermediates of porcine kidney D-amino acid oxidase reconstituted with 13C-enriched flavin adenine dinucleotide.

J. Biochem. 102(6) , 1345-54, (1987)

The 13C-NMR spectra of the reaction intermediates of D-amino acid oxidase (DAO) were measured with DAO reconstituted with FAD in which the 2-, 4-, 4a-, and 10a-positions of the isoalloxazine moiety were selectively 13C-enriched. The reaction intermediates use...

Vicine and convicine in common vetch (Vicia sativa) seeds enhance beta-cyanoalanine toxicity in male broiler chicks.

Int. J. Toxicol. 21(3) , 201-9, (2002)

Two studies were conducted to investigate the effects of feeding raw and water-soaked vetch seeds to male broiler chicks on performance, organ weights, and blood parameters. Intact and ground vetch seeds were soaked in water (1:5) at room temperature for 24 h...

Enzyme-activated inhibition of bacterial D-amino acid transaminase by beta-cyano-D-alanine.

Biochem. Biophys. Res. Commun. 122(2) , 485-91, (1984)

beta-Cyano-D-alanine is an efficient suicide substrate (Ki = 10 microM) of D-amino acid transaminase. This apparent inactivation is temperature dependent: it is irreversible at 10 degrees C or below and becomes progressively reversible at higher temperatures....

The effect of nalidixic acid, cinoxacin, and beta-cyanoalanine on cultured chondrocytes.

Arthritis Rheum. 31(3) , 455-6, (1988)