GW2974
GW2974结构式
|
常用名 | GW2974 | 英文名 | GW2974 |
|---|---|---|---|---|
| CAS号 | 202272-68-2 | 分子量 | 395.46 | |
| 密度 | N/A | 沸点 | 645.6ºC at 760 mmHg | |
| 分子式 | C23H21N7 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 344.3ºC |
|
Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/β-catenin signaling.
Mol. Biol. Cell 22 , 1121-1134, (2011) Desmocollin-2 (Dsc2) and desmoglein-2 (Dsg2) are transmembrane cell adhesion proteins of desmosomes. Reduced expression of Dsc2 has been reported in colorectal carcinomas, suggesting that Dsc2 may play a role in the development and/or progression of colorecta... |
|
|
Gene network dynamics controlling keratinocyte migration.
Mol. Syst. Biol. 4 , 199, (2008) Translation of large-scale data into a coherent model that allows one to simulate, predict and control cellular behavior is far from being resolved. Assuming that long-term cellular behavior is reflected in the gene expression kinetics, we infer a dynamic gen... |
|
|
Association of constitutively activated hepatocyte growth factor receptor (Met) with resistance to a dual EGFR/Her2 inhibitor in non-small-cell lung cancer cells.
Br. J. Cancer 100 , 941-9, (2009) There is a pressing need to identify new drug targets and novel approaches for treatment of non-small-cell lung carcinoma (NSCLC). Members of the epidermal growth factor receptor (EGFR) and Met receptor families have been identified as important molecular tar... |