1-甲基环丙烷-1-羧酸
1-甲基环丙烷-1-羧酸结构式
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常用名 | 1-甲基环丙烷-1-羧酸 | 英文名 | 1-Methylcyclopropanecarboxylic acid |
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| CAS号 | 6914-76-7 | 分子量 | 100.116 | |
| 密度 | 1.283 | 沸点 | 183.5±8.0 °C at 760 mmHg | |
| 分子式 | C5H8O2 | 熔点 | 30-32 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 184 °F | |
| 符号 |
GHS05 |
信号词 | Danger |
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Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3.
J. Biol. Chem. 286(12) , 10628-40, (2011) Free fatty acid receptor 2 (FFA2; GPR43) is a G protein-coupled seven-transmembrane receptor for short-chain fatty acids (SCFAs) that is implicated in inflammatory and metabolic disorders. The SCFA propionate has close to optimal ligand efficiency for FFA2 an... |
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Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs.
FASEB J. 26 , 4951-65, (2012) When it is difficult to develop selective ligands within a family of related G-protein-coupled receptors (GPCRs), chemically engineered receptors activated solely by synthetic ligands (RASSLs) are useful alternatives for probing receptor function. In the pres... |
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