邻氨基苯甲醛
邻氨基苯甲醛结构式
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常用名 | 邻氨基苯甲醛 | 英文名 | Formylaniline |
|---|---|---|---|---|
| CAS号 | 529-23-7 | 分子量 | 121.137 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 258.7±23.0 °C at 760 mmHg | |
| 分子式 | C7H7NO | 熔点 | 38°C | |
| MSDS | 中文版 美版 | 闪点 | 110.2±22.6 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Chondrogenesis of human bone marrow mesenchymal stromal cells in highly porous alginate-foams supplemented with chondroitin sulfate.
Mater. Sci. Eng. C. Mater. Biol. Appl. 50 , 160-72, (2015) To overcome the limited intrinsic cartilage repair, autologous chondrocyte or bone-marrow-derived mesenchymal stromal cell (BM-MSC) was implanted into cartilage defects. For this purpose suitable biocompatible scaffolds are needed to provide cell retention, c... |
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B-ring-aryl substituted luotonin A analogues with a new binding mode to the topoisomerase 1-DNA complex show enhanced cytotoxic activity.
PLoS ONE 9(5) , e95998, (2014) Topoisomerase 1 inhibition is an important strategy in targeted cancer chemotherapy. The drugs currently in use acting on this enzyme belong to the family of the camptothecins, and suffer severe limitations because of their low stability, which is associated ... |
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The consequences of the isotope effect on proline dehydrogenation rates estimated by the tritium loss method.
Anal. Biochem. 203(2) , 191-200, (1992) Loss of tritium from a substrate is often used to estimate the rate of dehydrogenation. However, loss of 3H may be much slower than loss of H because of the tritium isotope effect. In order to assess the impact of the tritium isotope effect, loss of 3H from t... |
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Co-regulation of mitochondrial respiration by proline dehydrogenase/oxidase and succinate.
Amino Acids 48 , 859-72, (2016) Proline dehydrogenase/oxidase (PRODH/POX) is a mitochondrial protein critical to multiple stress pathways. Because of the roles of PRODH/POX in signaling, and its shared localization to the mitochondrial inner membrane with the electron transport chain (ETC),... |
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Functional specialization in proline biosynthesis of melanoma.
PLoS ONE 7 , e45190, (2012) Proline metabolism is linked to hyperprolinemia, schizophrenia, cutis laxa, and cancer. In the latter case, tumor cells tend to rely on proline biosynthesis rather than salvage. Proline is synthesized from either glutamate or ornithine; both are converted to ... |
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LC-MS and NMR characterization of the purple chromophore formed in the o-aminobenzaldehyde assay of dihydrodipicolinate synthase.
Bioorg. Med. Chem. 19(4) , 1535-40, (2011) The enzyme dihydrodipicolinate synthase (DHDPS) has been widely investigated as a target for new antibiotics. The o-aminobenzaldehyde (o-ABA) assay is routinely used as a highly specific, if qualitative, tool for DHDPS purification, whereby fractions containi... |
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Redox-neutral indole annulation cascades.
J. Am. Chem. Soc. 133(7) , 2100-3, (2011) Aminobenzaldehydes react with indoles in an unprecedented cascade reaction. This acid-catalyzed redox-neutral annulation proceeds via a condensation/1,5-hydride shift/ring-closure sequence. Polycyclic azepinoindoles and related compounds are obtained in a sin... |
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Synthesis and structure-activity relationships of o-sulfonamido-arylhydrazides as inhibitors of LL-diaminopimelate aminotransferase (LL-DAP-AT).
Org. Biomol. Chem. 10(30) , 5815-9, (2012) Recently, LL-diaminopimelate aminotransferase (LL-DAP-AT), a pyridoxal-5'-phosphate (PLP)-dependent enzyme, was reported to catalyze a key step in the biosynthesis of L-lysine in plants and Chlamydia. Previous screening of a 29,201-compound library against LL... |
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Aminoindolines versus quinolines: mechanistic insights into the reaction between 2-aminobenzaldehydes and terminal alkynes in the presence of metals and secondary amines.
J. Org. Chem. 77(14) , 6179-85, (2012) DFT computational studies in the cyclization of aminoalkyne (see structure), which is generated in situ by 2-aminobenzaldehydes and terminal alkynes in the presence of metals and secondary amines, has been investigated. The study revealed that the mode of cyc... |
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Zn(OTf)2-catalyzed reactions of ethenetricarboxylates with 2-aminobenzaldehydes leading to tetrahydroquinoline derivatives.
J. Org. Chem. 75(4) , 1188-96, (2010) Quinolines are an important class of compounds, and the development of new efficient synthetic strategies for the construction of quinolines is of considerable interest. Zinc triflate catalyzed cyclization of ethenetricarboxylate derivatives with 2-aminobenza... |