异烟酰氯盐酸盐
异烟酰氯盐酸盐结构式
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常用名 | 异烟酰氯盐酸盐 | 英文名 | ISONICOTINOYL CHLORIDE HYDROCHLORIDE |
|---|---|---|---|---|
| CAS号 | 39178-35-3 | 分子量 | 178.016 | |
| 密度 | 1.297g/cm3 | 沸点 | 252.9ºC at 760 mmHg | |
| 分子式 | C6H5Cl2NO | 熔点 | 159-161 °C(lit.) | |
| MSDS | 美版 | 闪点 | 106.8ºC | |
| 符号 |
GHS05 |
信号词 | Danger |
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Direct oxidation and covalent binding of isoniazid to rodent liver and human hepatic microsomes: humans are more like mice than rats.
Chem. Res. Toxicol. 25 , 2567-76, (2012) Isoniazid (INH) is associated with serious liver injury and autoimmunity. Classic studies in rats indicated that a reactive metabolite of acetylhydrazine is responsible for the covalent binding and toxicity of INH. Studies in rabbits suggested that hydrazine ... |
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Synthesis and characterization of 7, 16-dinicotinoyl-and 7, 16-diisonico-tinoyltetraaza [14] annulene and their nickel (II) and copper (II) complexes. Sakata K and Itoh M.
J. Heterocycl. Chem. 29(4) , 921-6, (1992)
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