肥大脱粒肽
肥大脱粒肽结构式
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常用名 | 肥大脱粒肽 | 英文名 | Mastoparan trifluoroacetate salt |
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| CAS号 | 72093-21-1 | 分子量 | 1478.91000 | |
| 密度 | 1.15g/cm3 | 沸点 | 1676.8ºC at 760 mmHg | |
| 分子式 | C70H131N19O15 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 967.9ºC |
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Axon targeting of the alpha 7 nicotinic receptor in developing hippocampal neurons by Gprin1 regulates growth.
J. Neurochem. 129(4) , 649-62, (2014) Cholinergic signaling plays an important role in regulating the growth and regeneration of axons in the nervous system. The α7 nicotinic receptor (α7) can drive synaptic development and plasticity in the hippocampus. Here, we show that activation of α7 signif... |
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The chloroplast calcium sensor CAS is required for photoacclimation in Chlamydomonas reinhardtii.
Plant Cell 23(8) , 2950-63, (2011) The plant-specific calcium binding protein CAS (calcium sensor) has been localized in chloroplast thylakoid membranes of vascular plants and green algae. To elucidate the function of CAS in Chlamydomonas reinhardtii, we generated and analyzed eight independen... |
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Identification of the thiol isomerase-binding peptide, mastoparan, as a novel inhibitor of shear-induced transforming growth factor β1 (TGF-β1) activation.
J. Biol. Chem. 288(15) , 10628-39, (2013) TGF-β1 is a disulfide-bonded homodimeric protein produced by platelets and other cells that plays a role in many physiologic and pathologic processes. TGF-β1 is secreted as an inactive large latent complex (LLC) comprised of TGF-β1, latency-associated peptide... |
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Quantification of protein-protein interactions with chemical cross-linking and mass spectrometry.
J. Proteome Res. 10(4) , 1528-37, (2011) Chemical cross-linking in combination with mass spectrometry has largely been used to study protein structures and protein-protein interactions. Typically, it is used in a qualitative manner to identify cross-linked sites and provide a low-resolution topologi... |
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A compact intermediate state of calmodulin in the process of target binding.
Biochemistry 51(19) , 3963-70, (2012) Calmodulin undergoes characteristic conformational changes by binding Ca(2+), which allows it to bind to more than 300 target proteins and regulate numerous intracellular processes in all eukaryotic cells. We measured the conformational changes of calmodulin ... |
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Heterotrimeric Gα(i) proteins are regulated by lipopolysaccharide and are anti-inflammatory in endotoxemia and polymicrobial sepsis.
Biochim. Biophys. Acta 1813(3) , 466-72, (2011) Previous studies have implicated a role of heterotrimeric Gα(i) proteins in lipopolysaccharide (LPS)-induced inflammatory responses. We hypothesized that Toll-like receptor (TLR) signaling regulates Gα(i) proteins, which are anti-inflammatory in endotoxemia a... |
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The Rho kinase inhibitor Y-27632 increases erythrocyte deformability and low oxygen tension-induced ATP release.
Am. J. Physiol. Heart Circ. Physiol. 301(5) , H1891-6, (2011) Low oxygen (O(2)) tension and mechanical deformation are stimuli for ATP release from erythrocytes. It has been shown previously that rabbit erythrocytes made less deformable with diamide, a thiol cross-linking agent, release less ATP in response to low O(2) ... |
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Characterization of heterotrimeric nucleotide-depleted Gαi-proteins by Bodipy-FL-GTPγS fluorescence anisotropy
Arch. Biochem. Biophys. 524(2) , 93-8, (2012) Highlights ► StrepII-tagged γ2-subunits for the purification of heterotrimeric G-proteins. ► Preparation of GDP-depleted αi. ► Real-time monitoring of Bodipy-FL-GTPγS binding. ► Instability of GDP-depleted αi at room temperature. ► Mn2+ accelerates nucleotide... |
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Structural and biological characterization of mastoparans in the venom of Vespa species in Taiwan.
Peptides 32(10) , 2027-36, (2011) Mastoparans, a family of small peptides, are isolated from the wasp venom. In this study, six mastoparans were identified in the venom of six Vespa species in Taiwan. The precursors of these mastoparans are composed of N-terminal signal sequence, prosequence,... |
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PUFA-dependent alteration of oxidative parameters of a canine mastocytoma cell line.
Acta Vet. Hung. 58(4) , 453-64, (2010) Mast cells play a key role in the immune response. Thereby, the balance of oxidative metabolism is of importance in mast cell mediator synthesis and release. Fatty acids may modify mast cell function in several ways. In this study, we investigated the influen... |