1-甲基哌嗪 二盐酸盐
1-甲基哌嗪 二盐酸盐结构式
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常用名 | 1-甲基哌嗪 二盐酸盐 | 英文名 | 1-Methylpiperazine dihydrochloride |
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| CAS号 | 34352-59-5 | 分子量 | 173.084 | |
| 密度 | N/A | 沸点 | 138ºC at 760 mmHg | |
| 分子式 | C5H14Cl2N2 | 熔点 | 246-250ºC(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 42.2ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Mechanistic insights into the Pd(BINAP)-catalyzed amination of aryl bromides: kinetic studies under synthetically relevant conditions.
J. Am. Chem. Soc. 124(47) , 14104-14, (2002) Kinetic studies using reaction calorimetry were carried out under synthetically relevant conditions to study the mechanism of the amination of bromobenzene with primary and secondary amines using Pd(2)(dba)(3)/BINAP mixtures as well as preformed (dba)Pd(BINAP... |
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Chalcogenides of the aminomethylphosphines derived from 1-methylpiperazine, 1-ethylpiperazine and morpholine: NMR, DFT and structural studies for determination of electronic and steric properties of the phosphines.
Dalton Trans. 39(32) , 7547-55, (2010) Chalcogenide derivatives of three aminomethylphosphines: P(CH2N(CH2CH2)2NCH3)3 (1), P(CH2N(CH2CH2)2NCH2CH3)3 (2) and P(CH2N(CH2CH2)2O)3 (3) were prepared: oxides--OP(CH2N(CH2CH2)2NCH3)3 (4), OP(CH2N(CH2CH2)2NCH2CH3)3 (5), OP(CH2N(CH2CH2)2O)3 (6), sulfides--SP... |
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The hydrolysis kinetics of monobasic and dibasic aminoalkyl esters of ketorolac.
Drug Dev. Ind. Pharm. 39(9) , 1346-56, (2013) Six aminoethyl and aminobutyl esters of ketorolac containing 1-methylpiperazine (MPE and MPB), N-acetylpiperazine (APE and APB) or morpholine (ME and MB), were synthesized and their hydrolysis kinetics were studied. The hydrolysis was studied at pH 1 to 9 (fo... |
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1-Methyl-piperazine-1,4-diium tetra-chloridozincate hemihydrate.
Acta Crystallogr. Sect. E Struct. Rep. Online 67(Pt 11) , m1605, (2011) The crystal structure of the title compound, (C(5)H(14)N(2))[ZnCl(4)]·0.5H(2)O, is built up from discrete 1-methyl-piperazine-diium cations with chair conformation, tetrahedral tetrachloridozincate anions and uncoordinated solvent water mol-ecules linked toge... |
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IgE antibodies against piperazine and N-methyl-piperazine in two asthmatic subjects.
Int. Arch. Allergy Appl. Immunol. 79(3) , 259-62, (1986) The presence of specific IgE antibodies against conjugates between human serum albumin and piperazine, a compound previously known to cause occupational asthma, and N-methyl-piperazine, respectively, was demonstrated by RAST, RAST inhibition and skin prick te... |
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Bacterially catalysed N-nitrosation reactions and their relative importance in the human stomach.
Carcinogenesis 8(12) , 1907-12, (1987) Human exposure to endogenously formed N-nitroso compounds has frequently been suggested as a causative factor in carcinogenesis where this is related to chronic bacterial infection such as is seen in gastric achlorhydria. At least two distinct mechanisms of e... |
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Sequence-dependent variation in DNA minor groove width dictates orientational preference of Hoechst 33258 in A-tract recognition: solution NMR structure of the 2:1 complex with d(CTTTTGCAAAAG)(2).
Nucleic Acids Res. 28(3) , 728-35, (2000) The solution structure of the dodecamer duplex d(CTTTTGCAAAAG)(2)and its 2:1 complex with the bis -benzimidazole Hoechst 33258 has been investigated by NMR and NOE-restrained molecular dynamics (rMD) simulations. Drug molecules are bound in each of the two A-... |
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Photoaddition of N-substituted piperazines to C60: an efficient approach to the synthesis of water-soluble fullerene derivatives.
Chemistry 12(21) , 5569-77, (2006) An oxidative radical photoaddition of mono N-substituted piperazines to [60]fullerene was systematically investigated. Reactions of C60 with piperazines bearing bulky electron-withdrawing groups (2-pyridyl, 2-pyrimidinyl) were found to be the most selective a... |
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Influence of potassium fluoride on the syntheses of methylpiperazine-modified poly(vinyl chloride)s for use as fixed-site proton carrier membranes.
J. Biomed. Mater. Res. 39(4) , 667-72, (1998) Aminated poly(vinyl chloride) (PVC) membranes were prepared that had a Nernstian response over a wide range of pH. The reaction between PVC and methyl-piperazine (MePIP) in dimethylformamide (DMF) was studied over a wide range of time and temperature, and in ... |