2-羟基油酸
2-羟基油酸结构式
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常用名 | 2-羟基油酸 | 英文名 | Minerval |
|---|---|---|---|---|
| CAS号 | 56472-29-8 | 分子量 | 298.46100 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C18H34O3 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS05 |
信号词 | Danger |
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2-Hydroxyoleic acid induces ER stress and autophagy in various human glioma cell lines.
PLoS ONE 7 , e48235, (2012) 2-Hydroxyoleic acid is a synthetic fatty acid with potent anti-cancer activity which does not induce undesired side effects. However, the molecular and cellular mechanisms by which this compound selectively kills human glioma cancer cells without killing norm... |
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Sustained activation of sphingomyelin synthase by 2-hydroxyoleic acid induces sphingolipidosis in tumor cells.
J. Lipid Res. 54 , 1457-65, (2013) The mechanism of action of 2-hydroxyoleic acid (2OHOA), a potent antitumor drug, involves the rapid and specific activation of sphingomyelin synthase (SMS), leading to a 4-fold increase in SM mass in tumor cells. In the present study, we investigated the sour... |
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