(S)-2-((S)-2-氨基丙酰胺基)-3-(1H-咪唑-5-基)丙酸
(S)-2-((S)-2-氨基丙酰胺基)-3-(1H-咪唑-5-基)丙酸结构式
|
常用名 | (S)-2-((S)-2-氨基丙酰胺基)-3-(1H-咪唑-5-基)丙酸 | 英文名 | H-Ala-His-OH |
|---|---|---|---|---|
| CAS号 | 3253-17-6 | 分子量 | 226.23200 | |
| 密度 | 1.372g/cm3 | 沸点 | 629.5ºC at 760mmHg | |
| 分子式 | C9H14N4O3 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 334.5ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Carbonic anhydrase activators: high affinity isozymes I, II, and IV activators, incorporating a beta-alanyl-histidine scaffold.
J. Med. Chem. 45(2) , 284-91, (2002) A novel class of tight binding carbonic anhydrase (CA) activators was designed by using histamine and histidine as lead molecules. Carnosine (beta-Ala-His) derivatives were synthesized by reaction of appropriately derivatized beta-alanines with imidazole/carb... |
|
|
A potentiometric and 51V NMR study of the aqueous H+/H2VO4-/H2O2/L-alpha-alanyl-L-histidine system.
Chemistry 7(1) , 251-7, (2001) The speciation in the quaternary aqueous H+/H2VO4-/H2O2/L-alpha-alanyl-L-histidine (Ah) system has been determined from quantitative 51V NMR measurements and potentiometric data (glass electrode). The study was performed in 0.150 M Na(Cl) medium at 25 degrees... |
|
|
Investigation on the formation and the determination of gamma-glutamyl-beta-alanylhistidine and related isopeptide in the macromolecular fraction of beef soup stock.
J. Agric. Food Chem. 48(12) , 6317-24, (2000) To confirm the formation of gamma-glutamyl-beta-alanylhistidine and related peptide, a model solution (amide-containing amino acids and carnosine) has been heated, and the products are investigated. Spectroscopical analysis indicates that the major product fr... |
|
|
Sequence-dependent reactivity of model peptides with glyceraldehyde.
Carbohydr. Res. 189 , 49-63, (1989) Glyceraldehyde reacted faster with tripeptides than with dipeptides. The pH profiles of the reactions with tripeptides displayed optima in the range of 8.5-10.0, approximately 1-2 pH units higher than found with dipeptides. The second amino acid residue influ... |
|
|
Coordination features of difunctionalized beta-cyclodextrins with carnosine: ESI-MS and spectroscopic investigations on 6A,6D-di-(beta-alanyl-L-histidine)-6A,6D-dideoxy-beta-cyclodextrin and 6A,6C-di-(beta-alanyl-L-histidine)-6A,6C-dideoxy-beta-cyclodextrin and their copper(II) complexes.
J. Inorg. Biochem. 98(2) , 254-65, (2004) The synthesis and characterization of two beta-cyclodextrins (beta-CD) functionalized with two units of carnosine (beta-alanyl-L-histidine) through the amino group, 6A,6C-(beta-alanyl-L-histidine)-6A,6C-dideoxy-beta-cyclodextrin (ACCDAH) and 6A,6D-(beta-alany... |
|
|
Effect of carnosine and related compounds on the inactivation of human Cu,Zn-superoxide dismutase by modification of fructose and glycolaldehyde.
Biosci. Biotechnol. Biochem. 66 , 36-43, (2002) Glycolaldehyde, an intermediate of the Maillard reaction, and fructose, which is mainly derived from the polyol pathway, rapidly inactivate human Cu,Zn-superoxide dismutase (SOD) at the physiological concentration. We employed this inactivation with these car... |
|
|
Detection of the peptidyltransferase activity of a dipeptide, alanylhistidine, in the absence of ribosomes.
J. Biochem. 119(5) , 832-4, (1996) It was shown that a dipeptide, alanylhistidine, can act as a catalyst for the peptidyl transfer reaction in the absence of ribosomes between the amino acid moieties of phenylalanyl, lysyl, prolyl, and glycyl tRNAs depending on their model templates, poly U, p... |