2-硝基苯甲醚
一般危化品
2-硝基苯甲醚结构式
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常用名 | 2-硝基苯甲醚 | 英文名 | nitroanisole |
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| CAS号 | 91-23-6 | 分子量 | 153.135 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 277.0±0.0 °C at 760 mmHg | |
| 分子式 | C7H7NO3 | 熔点 | 9-12 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 127.0±21.8 °C | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger |
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Structure and performance of silica-based monolithic HPLC columns.
J. Sep. Sci. 31(14) , 2551-9, (2008) Silica-based monolithic columns were prepared for HPLC with systematic variations of the tetramethoxysilane (TMOS) and polyethylene oxide (PEO) content as reactants in a sol-gel process accompanied by phase separation. The resulting monoliths showed differenc... |
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Rat cytochromes P450 oxidize 2-nitrophenol, a human metabolite of carcinogenic 2-nitroanisole.
Neuro Endocrinol. Lett. 30 Suppl 1 , 46-51, (2009) 2-Nitrophenol (2-NP) is the major detoxification metabolite of an important industrial pollutant and a potent carcinogen, 2-nitroanisole (2-NA). Characterization of the products of 2-NP metabolism by rat hepatic microsomes containing cytochromes P450 (CYPs) a... |
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Identification of a genotoxic mechanism for 2-nitroanisole carcinogenicity and of its carcinogenic potential for humans.
Carcinogenesis 25(5) , 833-40, (2004) 2-Nitroanisole (2-NA) is an important industrial pollutant and a potent bladder carcinogen for rodents. The mechanism of its carcinogenicity was investigated in this study. Here we have used two independent methods, (32)P-post-labeling and (3)H-labeled 2-NA, ... |
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Human cytochrome-P450 enzymes metabolize N-(2-methoxyphenyl)hydroxylamine, a metabolite of the carcinogens o-anisidine and o-nitroanisole, thereby dictating its genotoxicity.
Mutat. Res. 726(2) , 160-8, (2011) N-(2-Methoxyphenyl)hydroxylamine is a component in the human metabolism of two industrial and environmental pollutants and bladder carcinogens, viz. 2-methoxyaniline (o-anisidine) and 2-methoxynitrobenzene (o-nitroanisole), and it is responsible for their gen... |
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Identification of rat cytochromes P450 metabolizing N-(2-methoxyphenyl)hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole.
Neuro Endocrinol. Lett. 31 Suppl 2 , 36-45, (2010) N-(2-methoxyphenyl)hydroxylamine is a human metabolite of two industrial and environmental pollutants and bladder carcinogens 2-methoxyaniline (o-anisidine) and 2-methoxynitrobenzene (o-nitroanisole). Metabolism of N-(2-methoxyphenyl)hydroxylamine by rat hepa... |
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Oxidative detoxication of carcinogenic 2-nitroanisole by human, rat and rabbit cytochrome P450.
Neuro Endocrinol. Lett. 27 Suppl 2 , 9-13, (2006) The detoxifying metabolism of a potent rodent carcinogen, 2-nitroanisole (2-NA) by human, rabbit and rat cytochromes P450 (P450) was investigated. Comparison between P450s of experimental animals and humans is essential for the extrapolation of animal carcino... |
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Carcinogenic pollutants o-nitroanisole and o-anisidine are substrates and inducers of cytochromes P450.
Biomed. Pap. Med. Fac. Univ. Palacky. Olomouc. Czech. Repub. 149(2) , 441-7, (2005) 2-Methoxyaniline (o-anisidine) and 2-methoxynitrobenzene (o-nitroanisole) are important pollutants and potent carcinogens for rodents. o-Anisidine is oxidized by microsomes of rats and rabbits to N-(2-methoxyphenyl)hydroxylamine that is also formed as the red... |
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Tumors of the bladder, kidney, and intestine of F344 rats and liver of B6C3F1 mice administered o-nitroanisole in feed.
Fundam. Appl. Toxicol. 30(1) , 1-12, (1996) o-Nitroanisole, a mutagenic intermediate used in the manufacture of azo dyes, was administered in feed for 2 years at concentrations of 0, 222, 666, or 2000 ppm to groups of 60 male and 60 female F344 rats. No significant increase in neoplasms occurred in the... |
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FT-IR and FT-Raman spectroscopic investigation, computed vibrational frequency analysis and IR intensity and Raman activity peak resemblance analysis on 2-nitroanisole using HF and DFT (B3LYP and B3PW91) calculations.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 83(1) , 8-16, (2011) Fourier-transform Raman and infrared spectra of 2-nitroanisole are recorded (4000-100 cm(-1)) and interpreted by comparison with respective theoretical spectra calculated using HF and DFT method. The geometrical parameters with C(S) symmetry, harmonic vibrati... |
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Effects of physical binding of o-Nitroanisole with feed upon its systemic availability in male F344 rats.
Bull. Environ. Contam. Toxicol. 47(1) , 152-9, (1991)
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