4-羟基苯硼酸
4-羟基苯硼酸结构式
|
常用名 | 4-羟基苯硼酸 | 英文名 | 4-Hydroxyphenylboronic acid |
|---|---|---|---|---|
| CAS号 | 71597-85-8 | 分子量 | 137.929 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 351.4±44.0 °C at 760 mmHg | |
| 分子式 | C6H7BO3 | 熔点 | >230 °C(lit.) | |
| MSDS | 美版 | 闪点 | 166.3±28.4 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Potent inhibitors of LpxC for the treatment of Gram-negative infections.
J. Med. Chem. 2nd ed., 55 , 914-923, (2012) In this paper, we present the synthesis and SAR as well as selectivity, pharmacokinetic, and infection model data for representative analogues of a novel series of potent antibacterial LpxC inhibitors represented by hydroxamic acid. |
|
|
Ishikawa, Shunpei; Manabe, Kei
Chem. Lett. 35 , 164-165, (2006)
|
|
|
Tetrahedron Lett. 48 , 845, (2007)
|
|
|
Synthetic approach to the chemical isostere of O-methyl honokiol Cui, M.; Kim, H. S.
Synlett 2nd ed., 23 , 311-313, (2012)
|
|
|
Highly selective palladium-catalyzed aminocarbonylation and cross-coupling reactions on a cavitand scaffold Csok, Z.; Takatsy, A.; Kollar, L.
Tetrahedron 12th ed., 68 , 2657-2661, (2012)
|
|
|
Bio-supported palladium nanoparticles as a phosphine-free catalyst for the Suzuki reaction in water Zhou, P.; et al.
RSC Advances 5th ed., 2 , 1759-1761, (2012)
|
|
|
Synthesis of Rod-Like Dendronized Polymers Containing G4 and G5 Ester Dendrons via Macromonomer Approach by Living ROMP Kim, K.O.; Choi, T-L.
ACS Macro Lett. 4th ed., 1 , 445-448, (2012)
|
|
|
Stereospecific palladium-catalyzed cross-coupling of (E)- and (Z)-alkenylsilanolates with aryl chlorides.
J. Am. Chem. Soc. 128 , 15958, (2006) The cross-coupling of geometrically defined (E)- and (Z)-alkenyl- and styrylsilanolates with a wide variety of aromatic and heteroaromatic chlorides has been achieved. Under catalysis by bulky, biphenyl-derived phosphines and allylpalladium chloride, the (pre... |
|
|
Efficient synthesis of 2,5-disubstituted tetrazoles via the Cu2O-catalyzed aerobic oxidative direct cross-coupling of N-H free tetrazoles with boronic acids.
Chem. Commun. (Camb.) 21th ed., 48 , 2719-2721, (2012) We present a new protocol that allows for the synthesis of 2,5-disubstituted tetrazoles via the direct coupling of N-H free tetrazoles and low toxic boronic acids in the presence of only a catalytic amount of Cu(2)O (5 mol%) as catalyst and 1 atm of environme... |
|
|
2-anilino-4-aryl-8H-purine derivatives as inhibitors of PDK1.
Bioorg. Med. Chem. Lett. 8th ed., 22 , 2880-2884, (2012) A series of 2-anilino substituted 4-aryl-8H-purines were prepared as potent inhibitors of PDK1, a serine-threonine kinase thought to play a role in the PI3K/Akt signaling pathway, a key mediator of cancer cell growth, survival and tumorigenesis. The synthesis... |