他米巴罗汀
他米巴罗汀结构式
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常用名 | 他米巴罗汀 | 英文名 | Tamibarotene |
|---|---|---|---|---|
| CAS号 | 94497-51-5 | 分子量 | 351.439 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 449.6±45.0 °C at 760 mmHg | |
| 分子式 | C22H25NO3 | 熔点 | 231-232ºC | |
| MSDS | 中文版 美版 | 闪点 | 225.7±28.7 °C |
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Retinoic acid acts as a selective human IgA switch factor.
Hum. Immunol. 75(8) , 923-9, (2014) Retinoic acid (RA) is known to have several functions that lead to a potent mucosal IgA response. Nevertheless, its exact role in human IgA synthesis has yet to be elucidated. Thus, we investigated the role of RA in promoting IgA isotype switching in human B ... |
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Retinoid signaling is necessary for, and promotes long-term memory formation following operant conditioning.
Neurobiol. Learn. Mem. 114 , 127-40, (2014) Retinoic acid, a metabolite of vitamin A, is proposed to play an important role in vertebrate learning and memory, as well as hippocampal-dependent synaptic plasticity. However, it has not yet been determined whether retinoic acid plays a similar role in lear... |
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Role of hematopoietic stem cell transplantation for relapsed acute promyelocytic leukemia: a retrospective analysis of JALSG-APL97.
Cancer Sci. 104(10) , 1339-45, (2013) For patients with relapsed acute promyelocytic leukemia (APL), all-trans retinoic acid-based salvage regimens can achieve second complete remission (CR2), but the optimal post-remission strategy for APL patients after CR2 remains unclear. Hematopoietic stem c... |
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A high-content imaging-based screening pipeline for the systematic identification of anti-progeroid compounds.
Methods 96 , 46-58, (2016) Hutchinson-Gilford Progeria Syndrome (HGPS) is an early onset lethal premature aging disorder caused by constitutive production of progerin, a mutant form of the nuclear architectural protein lamin A. The presence of progerin causes extensive morphological, e... |
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The Induction Effect of Am80 and TSA on ESC Differentiation via Regulation of Stra8 in Chicken.
PLoS ONE 10 , e0140262, (2015) Stra8 encodes stimulated by retinoic acid gene 8, a protein that is important for initiation of meiosis in mammals and birds. This study was aimed at identifying the active control area of chicken STRA8 gene core promoter, to screen optimum inducers of the ST... |
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Fluorescence spectrometric study on the interaction of tamibarotene with bovine serum albumin.
Luminescence 26(5) , 336-41, (2011) The interaction between tamibarotene and bovine serum albumin (BSA) was studied using fluorescence quenching technique and ultraviolet-visible spectrophotometry. The results of experiments showed that tamibarotene could strongly quench the intrinsic fluoresce... |
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Sustained molecular remission after arsenic trioxide and gemutuzumab ozogamicin in a pediatric patient with relapsed acute promyelocytic leukemia.
Pediatr. Hematol. Oncol. 29(2) , 170-2, (2012)
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Tamibarotene-induced low-grade reversible intravascular coagulation in a patient with acute promyelocytic leukemia.
Thromb. Res. 129(2) , 213-4, (2012)
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Editorial: CD38 and retinoids: a step toward a cure.
J. Leukoc. Biol. 90(2) , 217-9, (2011)
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Effects of tamibarotene for the treatment of adult T cell leukemia.
Ann. Hematol. 91(4) , 629-31, (2012)
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