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硫酸卡那霉素

硫酸卡那霉素结构式
硫酸卡那霉素结构式
品牌特惠专场
常用名 硫酸卡那霉素 英文名 Kanamycin sulfate
CAS号 25389-94-0 分子量 582.577
密度 1.3619 (rough estimate) 沸点 809.5ºC at 760 mmHg
分子式 C18H38N4O15S 熔点 250ºC
MSDS 中文版 美版 闪点 443.4ºC
符号 GHS08
GHS08
信号词 Danger

Synthesis and accumulation of aromatic aldehydes in an engineered strain of Escherichia coli.

J. Am. Chem. Soc. 136(33) , 11644-54, (2014)

Aromatic aldehydes are useful in numerous applications, especially as flavors, fragrances, and pharmaceutical precursors. However, microbial synthesis of aldehydes is hindered by rapid, endogenous, and redundant conversion of aldehydes to their corresponding ...

Intravenous peramivir inhibits viral replication, and leads to bacterial clearance and prevention of mortality during murine bacterial co-infection caused by influenza A(H1N1)pdm09 virus and Streptococcus pneumoniae.

Antiviral Res. 117 , 52-9, (2015)

Influenza virus infection increases susceptibility to bacterial infection and mortality in humans. Although the efficacy of approved intravenous peramivir, a neuraminidase (NA) inhibitor, against influenza virus infection has been reported, its efficacy again...

Engineering the genome of Thermus thermophilus using a counterselectable marker.

J. Bacteriol. 197(6) , 1135-44, (2015)

Thermus thermophilus is an extremely thermophilic bacterium that is widely used as a model thermophile, in large part due to its amenability to genetic manipulation. Here we describe a system for the introduction of genomic point mutations or deletions using ...

Metformin potentiates the anticancer effects of cisplatin under normoxic conditions in vitro.

Oncol. Rep. 33(2) , 744-50, (2014)

Metformin is a diabetes drug with anticancer properties. Several studies have investigated the effects of metformin combined with chemotherapeutic agents, with controversial results. This study evaluated the efficacy of combined metformin/cisplatin treatment ...

Recombinant immunoglobulin A specific for influenza A virus hemagglutinin: production, functional analysis, and formation of secretory immunoglobulin A.

Viral Immunol. 28(3) , 170-8, (2015)

Secretory immunoglobulin (Ig) A (SIgA), comprised of dimeric IgA and secretory component (SC), is believed to provide a defense mechanism on the mucosal surface. Influenza A virus (IAV) hemagglutinin (HA)-specific SIgA is thought to play an important role in ...

Study on interactions of aminoglycoside antibiotics with calf thymus DNA and determination of calf thymus DNA via the resonance Rayleigh scattering technique.

Luminescence 30 , 1159-66, (2015)

A simple and sensitive resonance Rayleigh scattering (RRS) spectra method was developed for the determination of calf thymus DNA (ctDNA). The enhanced RRS signals were based on the interactions between ctDNA and aminoglycoside antibiotics (AGs) including kana...

Aminoglycoside analysis in food of animal origin with a zwitterionic stationary phase and liquid chromatography-tandem mass spectrometry.

Anal. Chim. Acta 882 , 127-39, (2015)

In this study, fourteen highly polar aminoglycoside (AGs) antibiotics were selected. Various stationary phases were tested, including Obelisc R, ZIC-HILIC, BEH amide and aminopropyl. The nature of the stationary phase, mobile phase (water or buffer solutions ...

Engineering towards nitroreductase functionality in ene-reductase scaffolds.

ChemBioChem. 16(5) , 811-8, (2015)

Nitroreductases (NRs) and ene-reductases (ERs) both utilize flavin mononucleotide cofactors but catalyze distinct reactions. NRs reduce nitroaromatics, whereas ERs reduce unsaturated C=C double bonds, and these functionalities are known to somewhat overlap. R...

Purification and partial characterization of a thermostable antimicrobial protein from Bacillus subtilis FB123.

World J. Microbiol. Biotechnol. 31 , 1285-90, (2015)

Antimicrobial proteins/peptides have attracted much attention because of their potential use in the industrial setting. In the present study, a thermostable antimicrobial protein (BSAMP) was purified from the culture supernatant of Bacillus subtilis FB123 by ...

Colocalization and Sequential Enzyme Activity in Aqueous Biphasic Systems: Experiments and Modeling.

Biophys. J. 109 , 2182-94, (2015)

Subcellular compartmentalization of biomolecules and their reactions is common in biology and provides a general strategy for improving and/or controlling kinetics in metabolic pathways that contain multiple sequential enzymes. Enzymes can be colocalized in m...