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1-(3,6-二溴-9h-咔唑-9-基)-3-(二甲基氨基)-2-丙醇

1-(3,6-二溴-9h-咔唑-9-基)-3-(二甲基氨基)-2-丙醇结构式
1-(3,6-二溴-9h-咔唑-9-基)-3-(二甲基氨基)-2-丙醇结构式
品牌特惠专场
常用名 1-(3,6-二溴-9h-咔唑-9-基)-3-(二甲基氨基)-2-丙醇 英文名 Wiskostatin
CAS号 253449-04-6 分子量 426.146
密度 1.6±0.1 g/cm3 沸点 320.2±22.0 °C at 760 mmHg
分子式 C17H18Br2N2O 熔点 153-155ºC
MSDS 中文版 美版 闪点 147.4±22.3 °C
符号 GHS06
GHS06
信号词 Danger

Claudin-5 is involved in breast cancer cell motility through the N-WASP and ROCK signalling pathways.

J. Exp. Clin. Cancer Res 31 , 43, (2012)

Recent studies have shown dysregulation in TJ structure of several cancers including breast. Claudin-5 is a protein member of the TJ structure expressed in both endothelial and epithelial cells. This study examined the level of expression and distribution of ...

N-wasp is essential for the negative regulation of B cell receptor signaling.

PLoS Biol. 11 , e1001704, (2013)

Negative regulation of receptor signaling is essential for controlling cell activation and differentiation. In B-lymphocytes, the down-regulation of B-cell antigen receptor (BCR) signaling is critical for suppressing the activation of self-reactive B cells; h...

Coordinated oscillations in cortical actin and Ca2+ correlate with cycles of vesicle secretion.

Nat. Cell Biol. 14 , 1261-9, (2012)

The actin cortex both facilitates and hinders the exocytosis of secretory granules. How cells consolidate these two opposing roles was not well understood. Here we show that antigen activation of mast cells induces oscillations in Ca(2+) and PtdIns(4,5)P(2) l...