5(6)-羧基荧光素琥珀酰亚胺酯
5(6)-羧基荧光素琥珀酰亚胺酯结构式
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常用名 | 5(6)-羧基荧光素琥珀酰亚胺酯 | 英文名 | 5(6)-FAM SE |
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| CAS号 | 117548-22-8 | 分子量 | 473.39 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C25H15NO9 | 熔点 | 224ºC | |
| MSDS | 美版 | 闪点 | N/A |
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Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect.
J. Neurooncol. 122(1) , 21-33, (2015) The poor prognosis of patients with glioblastoma fuels the search for more effective therapeutic compounds. We previously hypothesised that the neuroleptic olanzapine may enhance antineoplastic effects of temozolomide the standard chemotherapeutic agent used ... |
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Modulation of endothelial cell integrity and inflammatory activation by commercial lipid emulsions.
Lipids Health Dis. 14 , 9, (2015) Thrombosis and immune dysfunction are two important complications that result from the administration of parenteral nutrition. Endothelial cells within the vasculature are crucial components necessary for maintenance of normal coagulation and immune function.... |
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Up-regulation of silent information regulator 2 (Sir2) is associated with amphotericin B resistance in clinical isolates of Leishmania donovani.
J. Antimicrob. Chemother. 70 , 1343-56, (2015) Silent information regulator 2 (Sir2) is involved in parasite survival and apoptosis. Here, we aimed to explore the involvement of Sir2 in amphotericin B (AmB) resistance mechanism in Leishmania donovani.The expression levels of Sir2, MDR1 and NAD(+) biosynth... |
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Eryptosis Indices as a Novel Predictive Parameter for Biocompatibility of Fe3O4 Magnetic Nanoparticles on Erythrocytes.
Sci. Rep. 5 , 16209, (2015) Fe3O4 magnetic nanoparticles (Fe3O4-MNPs) have been widely used in clinical diagnosis. Hemocompatibility of the nanoparticles is usually evaluated by hemolysis. However, hemolysis assessment does not measure the dysfunctional erythrocytes with pathological ch... |
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Anti-tumour effects of antibodies targeting the extracellular cysteine-rich region of the receptor tyrosine kinase EphB4.
Oncotarget 6 , 7554-69, (2015) EphB4 is a membrane-bound receptor tyrosine kinase (RTK) commonly over-produced by many epithelial cancers but with low to no expression in most normal adult tissues. EphB4 over-production promotes ligand-independent signaling pathways that increase cancer ce... |
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Loss of anchorage primarily induces non-apoptotic cell death in a human mammary epithelial cell line under atypical focal adhesion kinase signaling.
Cell Death Dis. 6 , e1619, (2015) Anchorage dependence of cellular growth and survival prevents inappropriate cell growth or survival in ectopic environments, and serves as a potential barrier to metastasis of cancer cells. Therefore, obtaining a better understanding of anchorage-dependent re... |
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In vivo evidence for platelet-induced physiological angiogenesis by a COX driven mechanism.
PLoS ONE 9(9) , e107503, (2014) We sought to determine a role for platelets in in vivo angiogenesis, quantified by changes in the capillary to fibre ratio (C:F) of mouse skeletal muscle, utilising two distinct forms of capillary growth to identify differential effects. Capillary sprouting w... |
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Sorafenib-induced defective autophagy promotes cell death by necroptosis.
Oncotarget 6 , 37066-82, (2015) Autophagy is one of the main cytoprotective mechanisms that cancer cells deploy to withstand the cytotoxic stress and survive the lethal damage induced by anti-cancer drugs. However, under specific conditions, autophagy may, directly or indirectly, induce cel... |
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STAT3 represents a molecular switch possibly inducing astroglial instead of oligodendroglial differentiation of oligodendroglial progenitor cells in Theiler's murine encephalomyelitis.
Neuropathol. Appl. Neurobiol. 41(3) , 347-70, (2015) Insufficient oligodendroglial differentiation of oligodendroglial progenitor cells (OPCs) is suggested to be responsible for remyelination failure and astroglial scar formation in Theiler's murine encephalomyelitis (TME). The aim of the present study is to id... |
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Exploring the size adaptability of the B ring binding zone of the colchicine site of tubulin with para-nitrogen substituted isocombretastatins.
Eur. J. Med. Chem. 100 , 210-22, (2015) We have synthesized and assayed dimethylaminophenyl, pyrrolidin-1-ylphenyl and carbazole containing phenstatins and isocombretastatins as analogues of the highly potent indoleisocombretastatins with extended or reduced ring sizes. This is an attempt to explor... |