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白三烯C3

白三烯C3结构式
白三烯C3结构式
品牌特惠专场
常用名 白三烯C3 英文名 Leukotriene C3
CAS号 77209-77-9 分子量 627.79000
密度 N/A 沸点 N/A
分子式 C30H49N3O9S 熔点 N/A
MSDS 中文版 美版 闪点 N/A

Conversion of 5,8,11-eicosatrienoic acid to leukotrienes C3 and D3.

J. Biol. Chem. 256 , 2275, (1981)

5,8,11-Eicosatrienoic acid was converted by mouse mastocytoma cells stimulated with ionophore A23187 to two slow reacting substances. These were characterized by spectroscopy and by chemical and enzymatic degradations as two geometrical isomers of 5-hydroxy-6...

Contractile activities of structural analogs of leukotrienes C and D: necessity of a hydrophobic region.

Proc. Natl. Acad. Sci. U. S. A. 78 , 3195, (1981)

Sixteen structural analogs of leukotrienes C and D were tested for their contractile activities on guinea pig pulmonary parenchymal strip and ileum. The analogs differed from the native structures in the position of either the thioether-linked peptide side ch...

Distribution and metabolism of 3H-labeled leukotriene C3 in the mouse.

J. Biol. Chem. 257(1) , 531-5, (1982)

The distribution of [5,6,8,9,11,12-3H6]leukotriene C3 in mice was determined by whole body autoradiography of sagittal sections. Tritium was rapidly eliminated from the circulation by uptake in liver and excretion in bile as well as by renal uptake and excret...

Metabolism of leukotriene C3 in the guinea pig. Identification of metabolites formed by lung, liver, and kidney.

J. Biol. Chem. 256(18) , 9573-8, (1981)

[5,6,8,9,11,12-3H6]Leukotriene C3 was converted to polar metabolites which ere excreted in feces and urine for 4-5 days after subcutaneous administration to guinea pigs. Lung homogenates converted leukotriene C3 to leukotriene D3. Liver and kidney homogenates...

Contractile activities of several cysteine-containing leukotrienes in the guinea-pig lung strip.

Eur. J. Pharmacol. 86(2) , 207-15, (1982)

Eight biosynthetically formed cysteine-containing leukotrienes dose dependently (0.01-100 nM) contracted parenchymal strips of guinea-pig lung. The response to the leukotrienes was slow in onset, remarkably long-lasting and often tachyphylactic upon repeated ...

Metabolism of leukotriene C3.

Adv. Prostaglandin. Thromboxane. Leukot. Res. 9 , 83-101, (1982)

Uptake and metabolism of leukotriene C3 by isolated rat organs and cells.

Biochem. Biophys. Res. Commun. 104(4) , 1434-40, (1982)

Rapid in vivo metabolism of leukotriene C3 in the monkey Macaca irus.

Biochem. Biophys. Res. Commun. 101(4) , 1109-15, (1981)

Metabolism and excretion of cysteinyl-leukotrienes.

Adv. Prostaglandin. Thromboxane. Leukot. Res. 16 , 383-96, (1986)

In vitro and in vivo experiments have demonstrated that a major pathway of metabolism of the glutathione containing leukotrienes involves modifications of the tripeptide substituent. The metabolic alterations are initiated by elimination of the N-terminal gam...

Biosynthesis and metabolism of leukotrienes.

Monogr. Allergy 18 , 265-71, (1983)