三羟甲基氨基甲烷盐酸盐
三羟甲基氨基甲烷盐酸盐结构式
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常用名 | 三羟甲基氨基甲烷盐酸盐 | 英文名 | Trometamol hydrochloride |
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| CAS号 | 1185-53-1 | 分子量 | 157.596 | |
| 密度 | 1.05 g/mL at 20 °C | 沸点 | 357ºC at 760 mmHg | |
| 分子式 | C4H12ClNO3 | 熔点 | 150-152 °C | |
| MSDS | 美版 | 闪点 | 169.7ºC |
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Novel in vitro platform to investigate myotube atrophy.
Anticancer Res. 35(4) , 2085-91, (2015) The electrical current exclusion (ECE) principle provides an alternative to common methods of cell diameter measurement and especially in atrophy and cancer associated cachexia research. C2C12 myoblasts were differentiated into myotubes and treated with 100 μ... |
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Advective hydrogel membrane chromatography for monoclonal antibody purification in bioprocessing.
Biotechnol. Prog. 31 , 974-82, (2015) Protein A chromatography is widely employed for the capture and purification of monoclonal antibodies (mAbs). Because of the high cost of protein A resins, there is a significant economic driving force to seek new downstream processing strategies. Membrane ch... |
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Highly sensitive DNA detection using cascade amplification strategy based on hybridization chain reaction and enzyme-induced metallization.
Biosens. Bioelectron. 66 , 520-6, (2014) A novel highly sensitive colorimetric assay for DNA detection using cascade amplification strategy based on hybridization chain reaction and enzyme-induced metallization was established. The DNA modified superparamagnetic beads were demonstrated to capture an... |
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Absolute protein quantification of clinically relevant cytochrome P450 enzymes and UDP-glucuronosyltransferases by mass spectrometry-based targeted proteomics.
J. Pharm. Biomed. Anal. 100 , 393-401, (2014) Cytochrome P450 (CYP) enzymes and UDP-glucuronosyltransferases (UGT) are major determinants in the pharmacokinetics of most drugs on the market. To investigate their impact on intestinal and hepatic drug metabolism, we developed and validated quantification m... |
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Single molecule array (Simoa) assay with optimal antibody pairs for cytokine detection in human serum samples.
Analyst 140 , 6277-82, (2015) Concentrations of cytokines in bodily fluids reflect the physiological or pathological state of the patient and can be used for prognosis, disease diagnosis or for monitoring therapeutic efficacy. However, in the bodily fluids of healthy or sub-healthy indivi... |
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EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques.
Nat. Commun. 6 , 8997, (2015) Alzheimer's disease (AD) is characterized by the transition of amyloid-β (Aβ) monomers into toxic oligomers and plaques. Given that Aβ abnormality typically precedes the development of clinical symptoms, an agent capable of disaggregating existing Aβ aggregat... |
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Glycan specificity of a testis-specific lectin chaperone calmegin and effects of hydrophobic interactions.
Biochim. Biophys. Acta 1840(9) , 2904-13, (2014) Testis-specific chaperone calmegin is required for the generation of normal spermatozoa. Calmegin is known to be a homologue of endoplasmic reticulum (ER) residing lectin chaperone calnexin. Although functional similarity between calnexin and calmegin has bee... |
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Par-3 modulates intestinal epithelial barrier function through regulating intracellular trafficking of occludin and myosin light chain phosphorylation.
J. Gastroenterol. 50 , 1103-13, (2015) Tight junctions play a critical role in the maintenance of intestinal barrier function. Partitioning-defective protein 3 (Par-3) can regulate intestinal barrier function through the modulation of tight junction assembly and cell polarity. However, the mechani... |
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Amperometric magnetoimmunosensor for ErbB2 breast cancer biomarker determination in human serum, cell lysates and intact breast cancer cells.
Biosens. Bioelectron. 70 , 34-41, (2015) A highly sensitive amperometric magnetoimmunosensor for the determination of ErbB2 protein, a well-known biomarker related to high-impact high-incidence diseases such as breast cancer, is described. A sandwich format involving the covalent immobilization of a... |
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An analysis of cosecretion and coexpression of gut hormones from male rat proximal and distal small intestine.
Endocrinology 156(3) , 847-57, (2015) Gut endocrine cells are generally thought to have distinct localization and secretory products. Recent studies suggested that the cells are highly related and have potential to express more than one hormone. We studied the coexpression and cosecretion of gut ... |