白屈菜酸
白屈菜酸结构式
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常用名 | 白屈菜酸 | 英文名 | Chelidonic acid |
|---|---|---|---|---|
| CAS号 | 99-32-1 | 分子量 | 184.10 | |
| 密度 | 1.821 g/cm3 | 沸点 | 471.3ºC at 760 mmHg | |
| 分子式 | C7H4O6 | 熔点 | 265 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 204.1ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Chelidonic acid and other conformationally restricted substrate analogues as inhibitors of rat brain glutamate decarboxylase.
Biochem. Pharmacol. 34 , 4145-4150, (1985) Twenty conformationally restricted analogues of glutamate including benzoic acids, hydroxy-benzoic acids, pyridine dicarboxylic acids, and pyran dicarboxylic acids were tested as inhibitors of glutamate decarboxylase from rat brain. Chelidonic acid, 2,6-pyrid... |
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Purification and characterization of dihydrodipicolinate synthase from pea.
Plant Physiol. 98(3) , 813-821., (1992) Dihydrodipicolinate synthase (EC 4.2.1.52), the first enzyme unique to lysine biosynthesis in bacteria and higher plants, has been purified to homogeneity from etiolated pea (Pisum sativum) seedlings using a combination of conventional and affinity chromatogr... |
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Tracer studies with 13C-labeled carbohydrates in cultured plant cells. Retrobiosynthetic analysis of chelidonic acid biosynthesis.
Phytochemistry 57(1) , 33-42, (2001) The biosynthesis of chelidonic acid was studied in cell suspension cultures of Leucojum aestivum. Cell cultures were supplied with [U-13C]glucose, [l-13C]glucose or [U-13Cs]ribose/ribulose in standard medium containing unlabeled glucose. 13C labeling patterns... |
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Inhibitory effects of chelidonic acid on IL-6 production by blocking NF-κB and caspase-1 in HMC-1 cells.
Immunopharmacol. Immunotoxicol. 33(4) , 614-9, (2011) Chelidonic acid (CA) is a γ-pyrone which is contained in the rhizome of Chelidonium majus L. It has multiple pharmacological effects including those of a mild analgesic, an antimicrobial, an oncostatic and a central nervous system sedative, but the anti-infla... |
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Beneficial effects of chelidonic acid on a model of allergic rhinitis.
Int. Immunopharmacol. 11(1) , 39-45, (2011) Chelidonic acid (CA) is known as an inhibitor of the rat brain glutamate decarboxylase. However, the pharmacological effects of CA in allergic reactions have not yet been defined. Here, we show the effects and the mechanism of CA in the ovalbumin (OVA)-sensit... |
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The therapeutic effect of chelidonic acid on ulcerative colitis.
Biol. Pharm. Bull. 35(5) , 666-71, (2012) Chelidonic acid (CA), a constituent of Chelidonium majus L., has many pharmacological effects, including mild analgesic and antimicrobial effects. However, the effects of CA on intestinal inflammation and the molecular mechanisms responsible are poorly unders... |
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Gad1 mRNA as a reliable indicator of altered GABA release from orexigenic neurons in the hypothalamus.
Eur. J. Neurosci. 42 , 2644-53, (2015) The strength of γ-aminobutyric acid (GABA)-mediated inhibitory synaptic input is a principle determinant of neuronal activity. However, because of differences in the number of GABA afferent inputs and the sites of synapses, it is difficult to directly assay f... |
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Statistically disordered short hydrogen bonds in (pipzH2)(cdoH)2 and a comparison with (pipzH2)(cdo)·H2O (pipz is piperazine and cdoH2 is chelidonic acid).
Acta Crystallogr. C 67(Pt 4) , o134-8, (2011) Two related proton-transfer compounds, namely piperazine-1,4-diium 4-oxo-4H-pyran-2,6-dicarboxylate monohydrate, C(4)H(12)N(2)(2+)·C(7)H(2)O(6)(2-)·H(2)O or (pipzH(2))(cdo)·H(2)O, (I), and piperazine-1,4-diium bis(6-carboxy-4-oxo-4H-pyran-2-carboxylate), C(4)... |
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Aqua [bis (2-pyridylmethyl) amine][chelidonato (1.5-)] copper (II) chelidonate (0.5-) monohydrate. Fainerman-Melnikova M, et al.
Acta Crystallogr. Sect. E Struct. Rep. Online 62(12) , m3582-m3584, (2006)
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