水杨酸毒扁豆碱
水杨酸毒扁豆碱结构式
|
常用名 | 水杨酸毒扁豆碱 | 英文名 | Physostigmine salicylate |
|---|---|---|---|---|
| CAS号 | 57-64-7 | 分子量 | 413.46700 | |
| 密度 | N/A | 沸点 | 393.5ºC at 760 mmHg | |
| 分子式 | C22H27N3O5 | 熔点 | 181-183 °C | |
| MSDS | 中文版 美版 | 闪点 | 191.8ºC | |
| 符号 |
GHS06 |
信号词 | Danger |
|
Possible interaction of cholinergic and GABAergic systems between MS and CA1 upon memory acquisition in rats.
Behav. Brain Res. 235(2) , 231-43, (2012) The present study explored the possibility that cholinergic and GABAergic systems of medial septum (MS) might influence acquisition of memory by regulation of acetylcholine (Ach) and γ-aminobutyric acid (GABA) receptors function in hippocampus and vice versa.... |
|
|
The effects of physostigmine infusion on patients with panic disorder.
Biol. Psychiatry 29(7) , 658-64, (1991) Nine patients who met both DSM-III and RDC criteria for panic disorder and nine age-matched normal controls received infusions of physostigmine. The patients and normal controls did not differ in either their self-reported or the observer-reported ratings of ... |
|
|
Development and optimization of a sublingual tablet formulation for physostigmine salicylate.
Acta. Pharm. 59(3) , 301-12, (2009) This study is aimed to design and optimize a sublingual tablet formulation of physostigmine salicylate, an effective drug in Alzheimer's disease and nerve gas poisoning, by means of the D-optimal experimental design methodology. Polyvinyl pyrrolidone, lactose... |
|
|
Liquid chromatographic analysis of physostigmine salicylate and its degradation products.
J. Pharm. Biomed. Anal. 18(6) , 939-45, (1999) A simple stability-indicating HPLC assay has been developed for physostigmine salicylate, capable of following its degradation. A 250 x 5 mm i.d. column packed with 10 microm Bondapak C18 was used, with a mobile phase of acetonitrile - ammonium acetate (pH 6.... |
|
|
Brain neurotransmitter systems mediating behavioral deficits produced by inescapable shock treatment in rats.
Brain Res. 447(1) , 122-32, (1988) The effect of inescapable footshock (IS) upon rats' motor activity (the open field and forced swim tests) was studied in rats subjected to drugs, and neurotoxin treatments, affecting their central neurotransmitter systems. The agonists of GABA-receptor comple... |
|
|
Toxicity study of continuous administration of physostigmine salicylate.
Pharmacol. Biochem. Behav. 31(3) , 627-31, (1988) The present study demonstrates that continuous administration with physostigmine salicylate (0.12 or 0.24 mg/kg/hr via mini-osmotic pumps) induces toxicities (e.g., body weight loss, decreased water consumption, tremors, decreased body temperatures, mortality... |
|
|
Tremorogenesis by physostigmine is unrelated to acetylcholinesterase inhibition: evidence for serotoninergic involvement.
Neurosci. Lett. 120(1) , 91-3, (1990) Studies were performed to bring out a serotoninergic involvement in physostigmine tremor, hitherto known to be working via the cholinergic system. 5-Hydroxytryptamine (5-HT) was estimated fluorimetrically after isolation on Sephadex G-10 and acetylcholinester... |
|
|
The pontomesencephalic tegmentum delays the peak latency of the visual evoked potential in rats.
Neurosci. Lett. 202(1-2) , 13-6, (1995) In previous experiments it was found that physostigmine application in unrestrained rats delayed the peak latency of the visual evoked potential (VEP). The present study was carried out to find the putative site that cholinergically mediates the latency delay... |
|
|
[Anticholinergic syndrome after postoperative dimenhydrinate administration].
HNO 49(12) , 1026-8, (2001) Appearance of an anticholinergic syndrome after treatment with drugs in therapeutic dosages is seldom reported in the literature. Based on a case report, the development and course of an anticholinergic syndrome after treatment with dimenhydrinate are describ... |
|
|
[The stabilization of physostigmine salicylate injection solutions. 2].
Pharmazie 45(10) , 783-5, (1990) In a long term test covering 4 years the potency of stabilizing agents for 0.04% physostigmine salicylate (1) solutions was studied under thermal loading. Thereby complex stabilizers were used as well as simple stabilizing agents. The most effective stabiliza... |