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双(2,2,2-三氟乙基)醚

双(2,2,2-三氟乙基)醚用途

Fluorothyl (Flurothyl) 是一种挥发性液体。

双(2,2,2-三氟乙基)醚名称

[ CAS 号 ]:
333-36-8

[ 中文名 ]:
2,2,2-三氟乙醚

[ 英文名 ]:
Fluorothyl

[中文别名 ]:

[英文别名 ]:

Bis(2,2,2-trifluoroethyl)ether
2,2,2-Trifluoroethyl Ether
Indoklon
Bis(2,2,2-trifluoroethyl) Ether
MFCD00010604
2,2,2-TRIFLUORO-N-(5-FLUOROTHIAZOL-2-YL)ACETAMIDE
HFE-356mf-f
Flurothyl
2,2,2-trifluorodiethyl ether
Hexafluorodiethyl ether

双(2,2,2-三氟乙基)醚生物活性

[ 描述 ]:

Fluorothyl (Flurothyl) 是一种挥发性液体。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

[参考文献]

[1]. Gao Y, et al. IL-33 Provides Neuroprotection through Suppressing Apoptotic, Autophagic and NF-κB-Mediated Inflammatory Pathways in a Rat Model of Recurrent Neonatal Seizure. Front Mol Neurosci. 2017 Dec 19;10:423.

[相关活性小分子]

双(2,2,2-三氟乙基)醚物理化学性质

[ 密度 ]:
1.404 g/mL at 25 °C(lit.)

[ 沸点 ]:
62-63 °C(lit.)

[ 分子式 ]:
C₄H₄F₆O

[ 分子量 ]:
182.06400

[ 闪点 ]:
35 °F

[ 精确质量 ]:
182.01700

[ PSA ]:
9.23000

[ LogP ]:
2.12760

[ 外观性状 ]:
液体;Colorless to Almost colorless clear liquid

[ 折射率 ]:
n20/D 1.300(lit.)

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、食品添加剂分开存放

双(2,2,2-三氟乙基)醚MSDS

详细MSDS(安全技术说明书)

双(2,2,2-三氟乙基)醚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KN3675000

CHEMICAL NAME :: Ether, bis(2,2,2-trifluoroethyl)

CAS REGISTRY NUMBER :: 333-36-8

BEILSTEIN REFERENCE NO. :: 1811927

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C4-H4-F6-O

MOLECULAR WEIGHT :: 182.08

WISWESSER LINE NOTATION :: FXFF1O1XFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1260 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 129,223,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 46 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 129,223,1960

双(2,2,2-三氟乙基)醚安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H315-H319-H335

[ 警示性声明 ]:
P210-P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ 危害码 (欧洲) ]:
F,Xi,T

[ 风险声明 (欧洲) ]:
11-36/37/38

[ 安全声明 (欧洲) ]:
S16-S26-S36

[ 危险品运输编码 ]:
UN 3271 3/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
KN3675000

[ 包装等级 ]:
II

[ 危险类别 ]:
3.1

[ 海关编码 ]:
2909199090

双(2,2,2-三氟乙基)醚上下游产品

双(2,2,2-三氟乙基)醚上游产品

双(2,2,2-三氟乙基)醚下游产品

双(2,2,2-三氟乙基)醚制备

以2,2,2-三氟代乙醇为原料制得。

双(2,2,2-三氟乙基)醚海关

[ 海关编码 ]: 2909199090

[ 中文概述 ]:
2909199090. 其他无环醚及其卤化衍生物（包括磺化，硝化或亚硝化衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

双(2,2,2-三氟乙基)醚文献

Spatiotemporal differences in the c-fos pathway between C57BL/6J and DBA/2J mice following flurothyl-induced seizures: A dissociation of hippocampal Fos from seizure activity.

Epilepsy Res. 109 , 183-96, (2014)

Significant differences in seizure characteristics between inbred mouse strains highlight the importance of genetic predisposition to epilepsy. Here, we examined the genetic differences between the se...

Early life status epilepticus and stress have distinct and sex-specific effects on learning, subsequent seizure outcomes, including anticonvulsant response to phenobarbital.

CNS Neurosci. Ther. 21(2) , 181-92, (2015)

Neonatal status epilepticus (SE) is often associated with adverse cognitive and epilepsy outcomes. We investigate the effects of three episodes of kainic acid-induced SE (3KA-SE) and maternal separati...

TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation.

Neuron 79(6) , 1086-93, (2013)

Dynamic changes in 5-methylcytosine (5mC) have been implicated in the regulation of gene expression critical for consolidation of memory. However, little is known about how these changes in 5mC are re...

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