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肉豆蔻酸

肉豆蔻酸用途

Myristic acid 是一种饱和的 14 碳脂肪酸,存在于大多数动植物脂肪中,特别是乳脂和椰子油,棕榈油和肉豆蔻油。

肉豆蔻酸名称

[ CAS 号 ]:
544-63-8

[ 中文名 ]:
肉豆蔻酸

[ 英文名 ]:
Myristic acid

[中文别名 ]:

[英文别名 ]:

triacontyl alcohol
Nutron
3H-myristic acid
myricyl
1-tetradecanoic acid
n-TETRADECANOIC ACID
tetradecoic acid
Tetradecanoic acid
WELL-BLOOM
n-Myristic acid

肉豆蔻酸生物活性

[ 描述 ]:

Myristic acid 是一种饱和的 14 碳脂肪酸,存在于大多数动植物脂肪中,特别是乳脂和椰子油,棕榈油和肉豆蔻油。

[ 相关类别 ]:

天然产物 >> 酸和醛

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[相关活性小分子]

肉豆蔻酸物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
319.6±5.0 °C at 760 mmHg

[ 熔点 ]:
52-54 °C(lit.)

[ 分子式 ]:
C₁₄H₂₈O₂

[ 分子量 ]:
228.371

[ 闪点 ]:
144.8±12.5 °C

[ 精确质量 ]:
228.208923

[ PSA ]:
37.30000

[ LogP ]:
6.09

[ 外观性状 ]:
白色固体

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.451

[ 储存条件 ]:
−20°C

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents, bases.

[ 水溶解性 ]:
<0.1 g/100 mL at 18 ºC

肉豆蔻酸MSDS

肉豆蔻酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QH4375000

CHEMICAL NAME :: Myristic acid

CAS REGISTRY NUMBER :: 544-63-8

BEILSTEIN REFERENCE NO. :: 0508624

LAST UPDATED :: 199701

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C14-H28-O2

MOLECULAR WEIGHT :: 228.42

WISWESSER LINE NOTATION :: QV13

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Human

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 43 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

MUTATION DATA

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 2500 ppb

REFERENCE :: ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 407,186,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1300 No. of Facilities: 1041 (estimated) No. of Industries: 15 No. of Occupations: 26 No. of Employees: 17023 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1300 No. of Facilities: 2926 (estimated) No. of Industries: 35 No. of Occupations: 48 No. of Employees: 72432 (estimated) No. of Female Employees: 29696 (estimated)

肉豆蔻酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
-

[ RTECS号 ]:
QH4375000

[ 海关编码 ]:
2915900090

肉豆蔻酸合成路线

肉豆蔻酸上下游产品

肉豆蔻酸上游产品

肉豆蔻酸下游产品

肉豆蔻酸制备

1.从椰子油、棕榈仁油所得的混合脂肪酸或混合脂肪酸的甲酯，旱灾行真空分馏可得十四酸。实验室制备可由甘油三（十四酸）酯和10%氢氧化钠溶液皂化，再用盐酸酸化得到游离的十四酸。也可由十四烷醇法制取。

2. 烟草：OR，18， 26， 44；FC，9， 15， 18， 40， 41.，43， 50；BU，9。

肉豆蔻酸海关

[ 海关编码 ]: 2915900090

[ 中文概述 ]:
2915900090. 其他饱和无环一元羧酸及其酸酐（酰卤、过氧）化物、过氧酸及其卤化、硝化、磺化、亚硝化衍生物. 增值税率:17.0%. 退税率:9.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

肉豆蔻酸文献

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Int. J. Pharm. 468(1-2) , 264-71, (2014)

An increasing human population requires a secure food supply and a cost effective, oral vaccine delivery system for livestock would help facilitate this end. Recombinant antigen adsorbed onto silica b...

Overcoming the equivalent-chain-length rule with pH-zone-refining countercurrent chromatography for the preparative separation of fatty acids.

Anal. Bioanal. Chem 407 , 5503-11, (2015)

Purification of individual fatty acids from vegetable oils by preparative liquid chromatography techniques such as countercurrent chromatography (CCC) is a challenging task due to the equivalent-chain...

Alkyl esters of L-ascorbic acid: Stability, surface behaviour and interaction with phospholipid monolayers.

J. Colloid. Interface Sci. 457 , 232-42, (2015)

L-ascorbic acid alkyl esters (ASCn) are molecules of pharmaceutical interest for their amphiphilic nature and proposed antioxidant power. In contrast to L-ascorbic acid, ASC(n) with different acyl cha...

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