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CI-943

CI-943用途

CI-943 是一种潜在的抗精神病药物。

CI-943名称

[ CAS 号 ]:
89239-35-0

[ 中文名 ]:
CI-943

[ 英文名 ]:
CI-943

[英文别名 ]:

CI 943

CI-943生物活性

[ 描述 ]:

CI-943 是一种潜在的抗精神病药物。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 神经疾病

[参考文献]

[1]. Meltzer LT, et al. CI-943, a potential antipsychotic agent. III. Evaluation of effects on dopamine neuronal activity. J Pharmacol Exp Ther. 1989 Oct;251(1):123-30.

[相关活性小分子]

CI-943物理化学性质

[ 密度 ]:
1.34g/cm3

[ 沸点 ]:
400.2ºC at 760 mmHg

[ 分子式 ]:
C₁₂H₁₇N₅

[ 分子量 ]:
231.29700

[ 闪点 ]:
195.8ºC

[ 精确质量 ]:
231.14800

[ PSA ]:
48.00000

[ LogP ]:
0.51510

[ 折射率 ]:
1.698

[ 储存条件 ]:
2-8℃

CI-943毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NJ5099300

CHEMICAL NAME :: 1H-Imidazo(1,2-c)pyrazolo(3,4-e)pyrimidine, 7,8-dihydro-8-ethyl-1,3,5-trimethyl-

CAS REGISTRY NUMBER :: 89239-35-0

LAST UPDATED :: 199510

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H17-N5

MOLECULAR WEIGHT :: 231.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 6150 mg/kg

SEX/DURATION :: male 9 week(s) pre-mating female 2 week(s) pre-mating - 3 week(s) after conception

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - other effects on male Reproductive - Maternal Effects - other effects

REFERENCE :: NETEEC Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987- Volume(issue)/page/year: 17,13,1995

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 6150 mg/kg

SEX/DURATION :: male 9 week(s) pre-mating female 2 week(s) pre-mating - 3 week(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - behavioral

REFERENCE :: NETEEC Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987- Volume(issue)/page/year: 17,13,1995

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 700 mg/kg

SEX/DURATION :: female 15-21 day(s) after conception lactating female 21 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - behavioral

REFERENCE :: NETEEC Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987- Volume(issue)/page/year: 17,13,1995

CI-943安全信息

[ 海关编码 ]:
2933990090

CI-943海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%