480-56-8

• 常用中文名：紅粉苔酸
• 常用英文名：Lecanoricacid
• CAS号：480-56-8
• 分子式：C₁₆H₁₄O₇
• 分子量：318.278
• 相关类别： 天然产物 酚类
• 发布时间：2018-02-11 08:00:00
• 更新时间：2026-07-13 17:52:58
• 蜡醛酸是一种从真菌中分离出来的组氨酸脱羧酶抑制剂。卵磷脂酸的抑制作用与组氨酸竞争,与磷酸吡哆醛非竞争。卵磷脂酸不抑制芳香族氨基酸脱羧酶[1]。

名称

• 中文名: 红粉苔酸
• 英文名: o-orsellinate depside
• 中文别名: 茶渍酸/茶渍衣酸/红粉苔酸; 茶渍酸; 4-((2,4-二羟基-6-甲基苯甲酰基)氧基)-2-羟基-6-甲基苯甲酸乙酯; 粉苔酸; 茶渍衣酸
• 英文别名: GLABRATIC ACID; 2-Hydroxy-4-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-6-methylbenzoic acid; 6-methyl-beta-resorcylicaci4-(6-methyl-beta-resorcylate); Lecic acid; lecanolic acid; 2,4-dihydroxy-6-methyl-benzoicaci4-cboxy-3-hydroxy-5-methylphenylest; Benzoic acid, 2,4-dihydroxy-6-methyl-, 4-cboxy-3-hydroxy-5-methylphenyl ester; 4-(2,4-dihydroxy-6-methyl-phenyl)cbonyloxy-2-hydroxy-6-methyl-benzoic acid; o-orsellinate dside; 4-[(2,4-Dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoic acid; 4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoic acid; Lecanoric acid, 10 mM in DMSO; lecanoric aicd; 4-CBOXY-3-HYDROXY-5-METHYLPHENYL 2,4-DIHYDROXY-5-METHYLBENZOATE; Lecanoric acid; 2,4-Dihydroxy-6-methylbenzoic acid 4-carboxy-3-hydroxy-5-methylphenyl ester; LECANORIC ACID; Lecanorsaeure; 6-Methyl-β-resorcylic acid 4-(6-methyl-β-resorcylate)

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 557.1±50.0 °C at 760 mmHg
• 熔点: 175-176ºC
• 分子式: C₁₆H₁₄O₇
• 分子量: 318.278
• 闪点: 208.3±23.6 °C
• 精确质量: 318.073944
• PSA: 124.29000
• LogP: 4.39
• 外观性状: 无色晶体
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.675
• 储存条件: 2-8℃，干燥，密闭

生物活性

• 描述: 蜡醛酸是一种从真菌中分离出来的组氨酸脱羧酶抑制剂。卵磷脂酸的抑制作用与组氨酸竞争,与磷酸吡哆醛非竞争。卵磷脂酸不抑制芳香族氨基酸脱羧酶[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Umezawa H, et al. Isolation of lecanoric acid, an inhibitor of histidine decarboxylase from a fungus. J Antibiot (Tokyo). 1974;27(8):587-596.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VH3709950 CHEMICAL NAME : beta-Resorcylic acid, 6-methyl-, 4-(6-methyl-beta-resorcylate) CAS REGISTRY NUMBER : 480-56-8 BEILSTEIN REFERENCE NO. : 2172778 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C16-H14-O7 MOLECULAR WEIGHT : 318.30 WISWESSER LINE NOTATION : QVR BQ F1 DOVR DQ B1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,587,1974

安全

• 危害码 (欧洲): Xi

上下游产品

上游产品  4
480-64-8 860752-66-5 623-11-0 548-89-0
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