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480-56-8

480-56-8 structure
480-56-8 structure
  • Name: Lecanoricacid
  • Chemical Name: o-orsellinate depside
  • CAS Number: 480-56-8
  • Molecular Formula: C16H14O7
  • Molecular Weight: 318.278
  • Catalog: Natural product Phenols
  • Create Date: 2018-02-11 08:00:00
  • Modify Date: 2026-07-13 17:52:58
  • Lecanoric acid is a histidine-decarboxylase inhibitor isolated from fungus. The inhibition by lecanoric acid is competitive with histidineand noncompetitive with pyridoxal phosphate. Lecanoric acid did not inhibit aromatic amino acid decarboxylase[1].
Name o-orsellinate depside
Synonyms GLABRATIC ACID
2-Hydroxy-4-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-6-methylbenzoic acid
6-methyl-beta-resorcylicaci4-(6-methyl-beta-resorcylate)
Lecic acid
lecanolic acid
2,4-dihydroxy-6-methyl-benzoicaci4-cboxy-3-hydroxy-5-methylphenylest
Benzoic acid, 2,4-dihydroxy-6-methyl-, 4-cboxy-3-hydroxy-5-methylphenyl ester
4-(2,4-dihydroxy-6-methyl-phenyl)cbonyloxy-2-hydroxy-6-methyl-benzoic acid
o-orsellinate dside
4-[(2,4-Dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoic acid
4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoic acid
Lecanoric acid, 10 mM in DMSO
lecanoric aicd
4-CBOXY-3-HYDROXY-5-METHYLPHENYL 2,4-DIHYDROXY-5-METHYLBENZOATE
Lecanoric acid
2,4-Dihydroxy-6-methylbenzoic acid 4-carboxy-3-hydroxy-5-methylphenyl ester
LECANORIC ACID
Lecanorsaeure
6-Methyl-β-resorcylic acid 4-(6-methyl-β-resorcylate)
Description Lecanoric acid is a histidine-decarboxylase inhibitor isolated from fungus. The inhibition by lecanoric acid is competitive with histidineand noncompetitive with pyridoxal phosphate. Lecanoric acid did not inhibit aromatic amino acid decarboxylase[1].
Related Catalog
References

[1]. Umezawa H, et al. Isolation of lecanoric acid, an inhibitor of histidine decarboxylase from a fungus. J Antibiot (Tokyo). 1974;27(8):587-596.
Density 1.5±0.1 g/cm3
Boiling Point 557.1±50.0 °C at 760 mmHg
Melting Point 175-176ºC
Molecular Formula C16H14O7
Molecular Weight 318.278
Flash Point 208.3±23.6 °C
Exact Mass 318.073944
PSA 124.29000
LogP 4.39
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.675

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VH3709950
CHEMICAL NAME :
beta-Resorcylic acid, 6-methyl-, 4-(6-methyl-beta-resorcylate)
CAS REGISTRY NUMBER :
480-56-8
BEILSTEIN REFERENCE NO. :
2172778
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H14-O7
MOLECULAR WEIGHT :
318.30
WISWESSER LINE NOTATION :
QVR BQ F1 DOVR DQ B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,587,1974
Hazard Codes Xi
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