25739-41-7

• 常用中文名：毡毛美洲茶素
• 常用英文名：Velutin
• CAS号：25739-41-7
• 分子式：C₁₇H₁₄O₆
• 分子量：314.289
• 相关类别： 天然产物 黄酮类化合物
• 发布时间：2016-06-11 05:15:03
• 更新时间：2024-01-05 15:18:03
• Velutin 是从槲寄生中提取的苷元,具有抑制黑色素生物合成的活性。Velutin 能通过 NF-κB 途径减少破骨细胞分化和下调 HIF-1α。

名称

• 中文名: 毡毛美洲茶素
• 英文名: 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxychromen-4-one
• 英文别名: 4',5-dihydroxy-3',7-dimethoxyflavone; 5,4'-dihydroxy-7,3'-dimethoxyflavone; Flavoyadorigenin B; 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4H-chromen-4-one; chrysoeriol-7-methyl ether; 5,4'-dihydroxy-7,3'-dimethoxylflavone; 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-; luteolin 7,3'-dimethyl ether; Velutin; 7,3'-di-O-methylluteolin

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 567.5±50.0 °C at 760 mmHg
• 分子式: C₁₇H₁₄O₆
• 分子量: 314.289
• 闪点: 213.1±23.6 °C
• 精确质量: 314.079041
• PSA: 89.13000
• LogP: 2.06
• 外观性状: 黄色粉末
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.646
• 储存条件: 2-8℃，干燥，密闭

生物活性

• 描述: Velutin 是从槲寄生中提取的苷元,具有抑制黑色素生物合成的活性。Velutin 能通过 NF-κB 途径减少破骨细胞分化和下调 HIF-1α。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Jung SH, et al. Velutin, an Aglycone Extracted from Korean Mistletoe, with Improved Inhibitory Activity against Melanin Biosynthesis. Molecules. 2019 Jul 12;24(14).

  [2]. Brito C, et al. Cytotoxicity and potential anti-inflammatory activity of velutin on RAW 264.7 cell line differentiation: Implications in periodontal bone loss. Arch Oral Biol. 2017 Nov;83:348-356

安全

• 危害码 (欧洲): Xi
• 海关编码: 2914509090

合成路线

1449692-19-6 ~% 25739-41-7

文献：Ahmad, Ateeque; Kim, Seung-Hyun; Ali, Mohd; Park, Inmyoung; Kim, Jin-Seog; Kim, Eun-Hye; Lim, Ju-Jin; Kim, Seul-Ki; Chung, Ill-Min Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 34 p. 8039 - 8048

1449692-20-9 ~% 25739-41-7

文献：Ahmad, Ateeque; Kim, Seung-Hyun; Ali, Mohd; Park, Inmyoung; Kim, Jin-Seog; Kim, Eun-Hye; Lim, Ju-Jin; Kim, Seul-Ki; Chung, Ill-Min Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 34 p. 8039 - 8048

1449692-19-6 ~% 58-86-6 25739-41-7 57-11-4

文献：Ahmad, Ateeque; Kim, Seung-Hyun; Ali, Mohd; Park, Inmyoung; Kim, Jin-Seog; Kim, Eun-Hye; Lim, Ju-Jin; Kim, Seul-Ki; Chung, Ill-Min Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 34 p. 8039 - 8048

1449692-20-9 ~% 58-86-6 25739-41-7 57-11-4

文献：Ahmad, Ateeque; Kim, Seung-Hyun; Ali, Mohd; Park, Inmyoung; Kim, Jin-Seog; Kim, Eun-Hye; Lim, Ju-Jin; Kim, Seul-Ki; Chung, Ill-Min Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 34 p. 8039 - 8048

41877-53-6 ~% 25739-41-7

文献：Geissman Australian Journal of Chemistry, 1958 , vol. 11, p. 376,381

491-70-3 ~% 520-34-3 491-71-4 25739-41-7 详细

文献：Brunet, Gunter; Ibrahim, Ragai K. Phytochemistry (Elsevier), 1980 , vol. 19, p. 741 - 746

1239-68-5 ~10% 62346-14-9 25739-41-7 29080-58-8 详细

文献：Geiger, Hans; Casteele, Karel Vande; Sumere, Christiaan F. Van Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1984 , vol. 39, # 3 p. 393 - 396

62346-14-9 ~5% 491-71-4 4712-12-3 25739-41-7 详细

文献：Geiger, Hans; Casteele, Karel Vande; Sumere, Christiaan F. Van Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1984 , vol. 39, # 3 p. 393 - 396

上下游产品

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41877-53-6 491-70-3 1239-68-5
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855-97-0

海关

海关编码	2914509090
中文概述	2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 丙酮报明包装
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%