1808266-58-1

• 常用中文名：EV-06
• 常用英文名：EV-06
• CAS号：1808266-58-1
• 分子式：C₁₃H₂₆ClNO₂S₂
• 分子量：327.934
• 发布时间：2021-01-06 18:57:17
• 更新时间：2024-09-18 03:59:22
• Alpha-Lipoic Acid Choline Ester, also known as alpha-LACE, EV-06 or UNR844, is a drug candidate potentially for the treatment of presbyopia. Alpha-LACE was designed to permeate biological membranes with the incorporation of the cationic choline head group. While lipoic acid does not permeate the cornea, the choline ester derivative of lipoic acid permeates the cornea, is hydrolyzed by corneal esterases and is transformed into the biologically active lipoic acid. LACE has been formulated into an ophthalmic solution to be applied twice daily as an eye-drop to treat presbyopia.

名称

• 英文名: -R-lipoic acid choline ester chloride
• 英文别名: 2-({5-[(3R)-1,2-Dithiolan-3-yl]pentanoyl}oxy)-N,N,N-trimethylethanaminium chloride; Ethanaminium, 2-[[5-[(3R)-1,2-dithiolan-3-yl]-1-oxopentyl]oxy]-N,N,N-trimethyl-, chloride (1:1); -R-lipoic acid choline ester chloride

物化性质

• 分子式: C₁₃H₂₆ClNO₂S₂
• 分子量: 327.934
• 精确质量: 327.109344