64372-56-1

• 常用中文名：1-[3-(二甲基氨基)丙基]-1-(4-氟苯基)-1,3-二氢-5-异苯并呋喃甲酰胺
• 常用英文名：1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarboxamide
• CAS号：64372-56-1
• 分子式：C₂₀H₂₃FN₂O₂
• 分子量：342.40700
• 相关类别： 分析化学 标准品 药典标准品和杂志标准品
• 发布时间：2018-12-29 20:19:40
• 更新时间：2026-07-09 12:21:00

名称

• 中文名: 1-[3-(二甲基氨基)丙基]-1-(4-氟苯基)-1,3-二氢-5-异苯并呋喃甲酰胺
• 英文名: 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carboxamide
• 中文别名: 西酞普兰相关物质A; 艾司西酞普兰杂质 (U); 西酞普兰杂质A; 西酞普兰杂质3(西酞普兰杂质A); 西酞普兰相关化合物A; CITALOPRAM 杂质 A; 1-[3-(二甲氨基)丙基]-1-(4-氟苯基)-1,3-二氢-5-异苯并呋喃甲酰胺; 草酸艾司西酞普兰杂质A; 西酞普兰(艾司西酞普兰)杂质A; 氢溴酸西酞普兰杂质A; 1-(3-(二甲氨基)丙基)-1-(4-氟苯基)-1,3-二氢异苯并呋喃-5-甲酰胺 (西酞普兰杂质); 西酞普兰酰胺
• 英文别名: Citalopram Related Compound A (1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofura; Citalopram Impurity 3(Citalopram Impurity A); (1RS)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-cboxamide (Citalopram-Amide); UNII-BP83XJ2B6A; Citalopram Related Compound A; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-cboxamide; Citalopram Impurity 3; Escitalopram Oxalate Impurity A; Citalopram Impurity 3（ Impurity A）; (S)-1-[3-Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3- dihydro-5-isobenzofuran-carbonitrile oxalate (ESCITALOPRAM OXALAT; CitalopraM IMpurity A; Escitalopram Impurity A; Citalopram Imp A; 5-Isobenzofurancboxamide, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro; EsCitalopram Impurity A (Citalopram Impurity A/ Citalopram Related Compound A/ Citalopram Amide); Citalopram Related Compound A (25 mg) (1-(3-(dimethylamino)propyl)-1-(4'-fluorophenyl)-1,3-dihydroisobenzofuran-5-cboxamide); Citalopram Impurity A/ Citalopram Related Compound A (EsCitalopram Impurity A/ Citalopram Amide); (1RS)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-cboxamide (Citalop; (1RS)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-cboxamide; Citalopram Hydrobromide Impurity A; (1RS)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-cbonitrilehydrobromide; Citalopram Impurity AQ: What is Citalopram Impurity A Q: What is the CAS Number of Citalopram Impurity A Q: What is the storage condition of Citalopram Impurity A Q: What e the applications of Citalopram Impurity A; 5-carboxamide citalopram; 1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-cboxamide (Citalopram Impurity); 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancboxamide; Citalopram(Escitalopram) Impurity A

物化性质

• 熔点: 126-128℃ (ethanol )
• 分子式: C₂₀H₂₃FN₂O₂
• 分子量: 342.40700
• 精确质量: 342.17400
• PSA: 56.55000
• LogP: 3.92440

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

59729-32-7 ~% 64372-56-1

文献：Sathyanarayana, Swargam; Kumar, Yatendra; Sharma, Tarum Kant; Biswas, Sujay; Vijayraghavan, Bakthavthsalan Patent: US2004/254385 A1, 2004 ; Location in patent: Page 3 ;

59729-33-8 ~48% 64372-56-1

文献：Banala, Ashwini K.; Zhang, Peng; Plenge, Per; Cyriac, George; Kopajtic, Theresa; Katz, Jonathan L.; Loland, Claus Juul; Newman, Amy Hauck Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9709 - 9724

103146-25-4 ~% 59729-33-8 64372-56-1

文献：MEDITAB SPECIALITIES PVT. LTD; WAIN, Christopher, Paul Patent: WO2005/12278 A2, 2005 ; Location in patent: Page/Page column 10-11 ;

59729-32-7 ~% 64372-56-1 1347761-10-7

文献：Sharma, Manav; Jawa, Parikshit R.; Gill, Ravinder S.; Bansal, Gulshan Journal of the Brazilian Chemical Society, 2011 , vol. 22, # 5 p. 836 - 848

59729-32-7 ~% 64372-56-1 63284-72-0 1347761-10-7

文献：Sharma, Manav; Jawa, Parikshit R.; Gill, Ravinder S.; Bansal, Gulshan Journal of the Brazilian Chemical Society, 2011 , vol. 22, # 5 p. 836 - 848