35475-03-7

• 常用中文名：5-氯噻吩-2-甲酸甲酯
• 常用英文名：Methyl-5-chlorothiophene-2-carboxylate
• CAS号：35475-03-7
• 分子式：C₆H₅ClO₂S
• 分子量：176.62100
• 发布时间：2018-05-07 08:00:00
• 更新时间：2026-07-15 11:08:13

名称

• 中文名: 5-氯-2-噻吩羧酸甲酯
• 英文名: methyl 5-chlorothiophene-2-carboxylate
• 中文别名: 5-氯噻吩-2-羧酸甲酯; 5-氯-2-噻吩甲酸甲酯; 5-氯噻吩-2-甲酸甲酯(利伐沙班杂质); 利伐沙班杂质; 利伐沙班杂质RB-7; 氯诺昔康杂质51
• 英文别名: QC-5846; 5-Chlorothiophene-2-cboxylic Acid Methyl Ester; Lornoxicam Impurity 51; Methyl 2-chloro-5-thiophenecboxylate (Rivoxaban Impurity); Methyl 5-chloro-2-thiophenecarboxylate; methyl 5-chlorothiophene-2-carboxylic acid; Rivoxaban Impurity; Methyl 5-chloro-2-thiophenecboxylate; 5-chloro-2-Thiophenecboxylic acid methyl ester; 2-chloro-5-methoxycarbonylthiophene; Rivoxaban Impurity RB-7; Methyl 5-chlorothiophene-2-cboxylate , Methyl 5-chlorothiophene-2-cboxylate; 5-chlorothiophene-2-carboxylic acid methyl ester; 5-chloro-2-Thiophene cbocylic acid methyl ester; Methyl 2-chloro-5-thiophenecboxylate; Methyl-5-chlorothiophene-2-cboxylate; methyl 2-(5-chloro-N-methyl-2-(pyridin-2-ylcbamoyl)thiophene-3-sulfonamido)acetate; 5-Chlor-thiophen-2-carbonsaeure-methylester; 2-Thiophenecboxylic acid, 5-chloro-, Methyl ester

物化性质

• 沸点: 226 °C
• 熔点: 18 °C
• 分子式: C₆H₅ClO₂S
• 分子量: 176.62100
• 闪点: 97 °C
• 精确质量: 175.97000
• PSA: 54.54000
• LogP: 2.18810
• 外观性状: 液体;White or Colorless to Light yellow to Light orange powder to lump to clear liquid
• 折射率: 1.56
• 储存条件: 室温，干燥

安全

• 海关编码: 2934999090

合成路线

67-56-1 24065-33-6 ~99% 35475-03-7

文献：SMITHKLINE BEECHAM CORPORATION Patent: WO2008/98104 A1, 2008 ; Location in patent: Page/Page column 109; 188 ; WO 2008/098104 A1

67-56-1 42518-98-9 ~% 35475-03-7

文献：MILLENNIUM PHARMACEUTICALS, INC. Patent: WO2006/2099 A2, 2006 ; Location in patent: Page/Page column 77 ; WO 2006/002099 A2

96-43-5 67-56-1 56-23-5 ~64% 35475-03-7

文献：Khusnutdinov; Shchadneva; Baiguzina; Mukminov; Mayakova; Smirnov; Dzhemilev Petroleum Chemistry, 2008 , vol. 48, # 6 p. 471 - 478

1003-09-4 67-56-1 56-23-5 ~0% 35475-03-7 详细

文献：Khusnutdinov; Shchadneva; Baiguzina; Mukminov; Mayakova; Smirnov; Dzhemilev Petroleum Chemistry, 2008 , vol. 48, # 6 p. 471 - 478

3437-95-4 67-56-1 56-23-5 ~0% 35475-03-7 详细

文献：Khusnutdinov; Shchadneva; Baiguzina; Mukminov; Mayakova; Smirnov; Dzhemilev Petroleum Chemistry, 2008 , vol. 48, # 6 p. 471 - 478

24065-33-6 ~% 35475-03-7

文献：Aitken, R. Alan; Bibby, Michael C.; Bielefeldt, Florian; Double, John A.; Laws, Andrea L.; Mathieu, Anne-Laure; Ritchie, Robert B.; Wilson, David W. J. Archiv der Pharmazie, 1998 , vol. 331, # 12 p. 405 - 411

7647-01-0 67-56-1 24065-33-6 ~% 35475-03-7

文献：Imoto et al. Nippon Kagaku Zasshi, 1956 , vol. 77, p. 804,807 Chem.Abstr., 1958 , p. 9066

上下游产品

上游产品  8
67-56-1 24065-33-6 42518-98-9 96-43-5
56-23-5 1003-09-4 3437-95-4 7647-01-0
下游产品  4
57800-76-7 366789-02-8 22353-82-8 89166-85-8

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%