2957-21-3

• 常用中文名：樱花亭
• 常用英文名：Sakuranetin
• CAS号：2957-21-3
• 分子式：C₁₆H₁₄O₅
• 分子量：286.28
• 相关类别： 天然产物 黄酮类化合物
• 发布时间：2018-05-20 08:00:00
• 更新时间：2026-07-05 13:05:21
• Sakuranetin 是一种大米黄酮类植物抗毒素,具有很强的抗真菌活性。Sakuranetin 具有抗炎和抗氧化作用,能够改善 LPS 诱导的急性肺损伤。

名称

• 中文名: 樱花亭
• 英文名: Sakuranetin
• 中文别名: 4,5-二羥-7-甲氧黃烷酮; 樱红素; 樱花素樱花亭; 恩杂鲁胺杂质55; 樱花素,樱花亭(带旋光数据); 樱花素,10 MM DMSO 溶液; (S)-5-羟基-2-(4-羟基苯基)-7-甲氧基苯并二氢吡喃-4-酮; Sakrinak 樱花亭; 櫻花精; 恩扎鲁他胺杂质55; 樱花素
• 英文别名: 4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-, (2S); Einecs -5; 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydrochromen-4-one; 4',5-Dihydroxy-7-methoxyflavanone; EINECS 220-980-5; 4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-, (S)- (9ci); (S)-(-)-4',5-dihydroxy-7-methoxyflavanone; 5,4'-DIHYDROXY-7-O-METHOXYFLAVANONE; Naringenin 7-O-methyl ether; (2S)-sakuranetin; 5,4''-DIHYDROXY-7-METHOXYFLAVANONE MONOHYDRATE; Ningen 7-methyl ether; 4',5-DIHYDROXY-7-METHOXYFLAVANONE; (S)-5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxychroman-4-one; Sakura Pavilion; naringenin 7-methylether; Sakrinak Sakuranetin; (S)-2,3-Dihydro-2-(4-hydroxyphenyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one; (2S)-5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydro-4H-chromen-4-one; 5,4''-DIHYDROXY-7-METHOXYFLAVANONE; Naringenin 7-methyl ether; Nsc; (-)-(S)-sakuranetin; 2α-(4-Hydroxyphenyl)-7-methoxy-5-hydroxy-2,3-dihydro-4H-1-benzopyran-4-one; SAKURANETIN(SH); (S)-2,3-Dihydro-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one; 4',5-DIHYDROXY-7-METHOXYFLAVONE; SAKURANETIN; 5,4'-dihydroxy-7-methoxyflavanone; (S) 5-hydroxy-2- (4-hydroxyphenyl) -7-methoxybenzopyran-4-one; Sakuranetin, 10 mM in DMSO; Enzalutamide Impurity 55; SAKURANETIN(P); 7-O-Methylnaringenin; Flavanone, 4',5-dihydroxy-7-methoxy-, (S)-(-)- (8ci); (S)-(-)-4',5-Dihydroxy-7-methoxy-flavanone; 7-O-Methylningenin; SAKURANETIN hplc; Ningenin 7-O-methyl ether; (S)-()-4′-5-Dihydroxy-7-methoxyflavanone

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 555.9±50.0 °C at 760 mmHg
• 熔点: 153-154ºC
• 分子式: C₁₆H₁₄O₅
• 分子量: 286.28
• 闪点: 212.4±23.6 °C
• 精确质量: 286.084137
• PSA: 75.99000
• LogP: 3.37
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.638
• 储存条件: 2-8℃

生物活性

• 描述: Sakuranetin 是一种大米黄酮类植物抗毒素,具有很强的抗真菌活性。Sakuranetin 具有抗炎和抗氧化作用,能够改善 LPS 诱导的急性肺损伤。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 真菌
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Hasegawa M, et al. Analysis on blast fungus-responsive characters of a flavonoid phytoalexin sakuranetin; accumulation in infected rice leaves, antifungal activity and detoxification by fungus. Molecules. 2014 Aug 4;19(8):11404-18.

  [2]. Bittencourt-Mernak MI, et al. Prophylactic and therapeutic treatment with the flavonone sakuranetin ameliorates LPS-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L217-L230.

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 危害码 (欧洲): Xn
• 风险声明 (欧洲): 22
• 危险品运输编码: NONH for all modes of transport