樱花亭

• 常用名: 樱花亭
• 英文名: Sakuranetin
• CAS号: 2957-21-3
• 分子量: 286.28
• 密度: 1.4±0.1 g/cm3
• 沸点: 555.9±50.0 °C at 760 mmHg
• 分子式: C₁₆H₁₄O₅
• 熔点: 153-154ºC
• 闪点: 212.4±23.6 °C
• 符号: GHS07
• 信号词: Warning

樱花亭用途

Sakuranetin 是一种大米黄酮类植物抗毒素,具有很强的抗真菌活性。Sakuranetin 具有抗炎和抗氧化作用,能够改善 LPS 诱导的急性肺损伤。

樱花亭名称

• 中文名: 樱花亭
• 英文名: Sakuranetin
• 中文别名: 樱花素 | 4,5-二羥-7-甲氧黃烷酮

樱花亭生物活性

• 描述: Sakuranetin 是一种大米黄酮类植物抗毒素,具有很强的抗真菌活性。Sakuranetin 具有抗炎和抗氧化作用,能够改善 LPS 诱导的急性肺损伤。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 真菌
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Hasegawa M, et al. Analysis on blast fungus-responsive characters of a flavonoid phytoalexin sakuranetin; accumulation in infected rice leaves, antifungal activity and detoxification by fungus. Molecules. 2014 Aug 4;19(8):11404-18.

  [2]. Bittencourt-Mernak MI, et al. Prophylactic and therapeutic treatment with the flavonone sakuranetin ameliorates LPS-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L217-L230.

樱花亭物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 555.9±50.0 °C at 760 mmHg
• 熔点: 153-154ºC
• 分子式: C₁₆H₁₄O₅
• 分子量: 286.28
• 闪点: 212.4±23.6 °C
• 精确质量: 286.084137
• PSA: 75.99000
• LogP: 3.37
• InChIKey: DJOJDHGQRNZXQQ-AWEZNQCLSA-N
• SMILES: COc1cc(O)c2c(c1)OC(c1ccc(O)cc1)CC2=O
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.638
• 储存条件: 2-8℃

樱花亭安全信息

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 危害码 (欧洲): Xn
• 风险声明 (欧洲): 22
• 危险品运输编码: NONH for all modes of transport

樱花亭靶点实验

查看更多实验

实验名称：Antitubercular activity against Mycobacterium tuberculosis H37Rv after 2 weeks by aga... 来源：ChEMBL 靶标：Mycobacterium tuberculosis External Id：CHEMBL959623

实验名称：Antifungal activity against Cladosporium sphaerospermum assessed as minimum concentra... 来源：ChEMBL 靶标：Cladosporium sphaerospermum External Id：CHEMBL995709

实验名称：Antifungal activity against Cladosporium cladosporioides assessed as minimum concentr... 来源：ChEMBL 靶标：Cladosporium cladosporioides External Id：CHEMBL995708

实验名称：Experimentally measured binding affinity data (Ki) for protein-ligand complexes deriv... 来源：Shanghai Institute of Organic Chemistry 靶标：N/A External Id：PDBbind-Ki for protein-ligand complexes

实验名称：Trypanocidal activity against Trypanosoma cruzi Y strain trypomastigotes infected in ... 来源：ChEMBL 靶标：Trypanosoma cruzi External Id：CHEMBL1031829

实验名称：Human A2A receptor (Adenosine receptors) 来源：IUPHAR-DB 靶标：A2A receptor (Adenosine receptors) [Homo sapiens] External Id：19_Human

实验名称：Rat A1 receptor (Adenosine receptors) 来源：IUPHAR-DB 靶标：A1 receptor (Adenosine receptors) [Rattus norvegicus] External Id：18_Rat

实验名称：Human A3 receptor (Adenosine receptors) 来源：IUPHAR-DB 靶标：A3 receptor (Adenosine receptors) [Homo sapiens] External Id：21_Human

实验名称：Induction of apoptosis in human drug-sensitive LoVo cells assessed as necrotic cells ... 来源：ChEMBL 靶标：LoVo External Id：CHEMBL2167176

实验名称：Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells afte... 来源：ChEMBL 靶标：Nitric oxide synthase, inducible External Id：CHEMBL1930163

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樱花亭英文别名

• 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydrochromen-4-one
• 4',5-Dihydroxy-7-methoxyflavanone
• (S)-(-)-4',5-dihydroxy-7-methoxyflavanone
• 4',5-DIHYDROXY-7-METHOXYFLAVONE
• Naringenin 7-O-methyl ether
• 5,4'-dihydroxy-7-methoxyflavanone
• (2S)-sakuranetin
• 7-O-Methylnaringenin
• naringenin 7-methylether
• (S)-(-)-4',5-Dihydroxy-7-methoxy-flavanone
• (2S)-5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydro-4H-chromen-4-one
• Sakuranetin
• Naringenin 7-methyl ether
• EINECS 220-980-5