856676-23-8

856676-23-8结构式

中文名	非诺贝特酸胆碱盐
英文名	2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate,2-hydroxyethyl(trimethyl)azanium
中文别名	非诺贝特胆碱盐 Choline 普鲁脂芬非诺贝特胆碱,10 MM DMSO 溶液 2-((4 - 氯)苯氧基)-2 - 甲基丙基-2 - 羟基-N,N,N - 三乙基苯酚乙铵盐非诺贝特胆碱非诺贝特酸胆碱 2-(4-(4-氯苯甲酰基)苯氧基)-2-甲基丙酸 2-羟基-N,N,N-三甲基乙铵盐非诺贝酸胆碱胆碱非诺贝特对照品非诺贝特杂质8(非诺贝特胆碱) 胆碱非诺贝特
英文别名	Choline Fenofibrate, 10 mM in DMSO 2-Hydroxy-N,N,N-triMethylethanaMiniuM 2-[4-(4-chlorobenzoyl)phenoxy] -2-Methylpropanoate Fenofibrate de choline 2-hydroxy-N,N,N-trimethyl, 2-{4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate Trilipix Fenofibrate Impurity 8(Choline Fenofibrate) Choline fenofibrate (ABT-335) Abt UNII-4BMH7IZT98 ABT-335 Choline Fenofibrate (CFRC-3) Fenofibric acid choline saltQ: What is Fenofibric acid choline salt Q: What is the CAS Number of Fenofibric acid choline salt Q: What is the storage condition of Fenofibric acid choline salt Q: What e the applications of Fenofibric acid choline salt Fenofibric acid choline salt fenofibric acid choline salt Unii-4bmh7izt98 2-Hydroxy-N,N,N-trimethylethan-1-aminium 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate Unii-4bmh7izt98 //BP tert-butylN-(1-amino-2-oxoazetidin-7-yl)cbamate Choline fenofibrate Unii-4bmh7izt98 856-8

描述	Choline Fenofibrate (ABT-335)是fenofibric acid的胆碱盐,可与rosuvastatin结合作用于血脂异常。
相关类别	信号通路 >> 代谢酶/蛋白酶 >> 细胞色素P450 研究领域 >> 心血管疾病
参考文献	[1]. Jones PH, Bays HE, Davidson MH et al. Evaluation of a new formulation of fenofibric acid, ABT-335, co-administered with statins : study design and rationale of a phase III clinical programme. Clin Drug Investig. 2008;28(10):625-34. [2]. Mohiuddin SM, Pepine CJ, Kelly MT et al. Efficacy and safety of ABT-335 (fenofibric acid) in combination with simvastatin in patients with mixed dyslipidemia: a phase 3, randomized, controlled study. Am Heart J. 2009 Jan;157(1):195-203. [3]. Zhu T, Awni WM, Hosmane B et al. ABT-335, the choline salt of fenofibric acid, does not have a clinically significant pharmacokinetic interaction with rosuvastatin in humans. J Clin Pharmacol. 2009 Jan;49(1):63-71. [4]. Goldberg AC, Bays HE, Ballantyne CM et al. Efficacy and safety of ABT-335 (fenofibric acid) in combination with atorvastatin in patients with mixed dyslipidemia. Am J Cardiol. 2009 Feb 15;103(4):515-22. [5]. Campbell J, Mohiuddin SM. The role of a new formulation of fenofibric acid in the treatment of mixed dyslipidemia in type 2 diabetes. Drugs Today (Barc). 2010 Oct;46(10):757-64.