中文名 | 3-氧代-12-烯-28-齐墩果酸 |
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英文名 | (4aS,6aR,6aS,6bR,8aR,12aR,14bS)-2,2,6a,6b,9,9,12a-heptamethyl-10-oxo-3,4,5,6,6a,7,8,8a,11,12,13,14b-dodecahydro-1H-picene-4a-carboxylic acid |
中文别名 |
3-氧代-12-齐墩果烯-28-羧酸
齐墩果酮酸 |
英文别名 |
oleanoic acid
3-oxooleana-12-en-28-oic acid Olean-12-en-28-oic acid,3-oxo oleanonic acid 3-oxo-oleanolic acid 3-Oxoolean-12-en-28-oic acid Olean-12-en-28-oic acid, 3-oxo- 3-keto oleanolic acid 3-oxo-olean-12-en-28-oic acid |
描述 | Oleanonic acid是一种三萜,可以抑制HIV-1对细胞的感染。起抑制HIV-1体外感染PBMC,自然感染PBMC和单核细胞/巨噬细胞的EC50分别为22.7mM,24.6mM和57.4mM。除此之外,它可以抑制鼠腹腔白细胞产生白三烯B4,IC50为17μm。 |
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相关类别 | |
参考文献 |
密度 | 1.1±0.1 g/cm3 |
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沸点 | 551.7±50.0 °C at 760 mmHg |
分子式 | C30H46O3 |
分子量 | 454.684 |
闪点 | 301.5±26.6 °C |
精确质量 | 454.344696 |
PSA | 54.37000 |
LogP | 8.48 |
蒸汽压 | 0.0±3.2 mmHg at 25°C |
折射率 | 1.552 |
储存条件 | -20°C |
~10% 17990-42-0 |
文献:Organic and Biomolecular Chemistry, , vol. 11, # 10 p. 1726 - 1738 |
~93% 17990-42-0 |
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~% 17990-42-0 |
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~% 17990-42-0 |
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~% 17990-42-0 |
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~% 17990-42-0 |
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