134877-42-2

• 常用中文名：2-脱氧-2,2-二氟-D-呋喃核糖基-3,5-二苯甲酰基-1-甲磺酸酯
• 常用英文名：2-Deoxy-2,2-difluoro-D-ribofuranose-3,5-dibenzoate-1-methanesulfonate
• CAS号：134877-42-2
• 分子式：C₂₀H₁₈F₂O₈S
• 分子量：456.414
• 发布时间：2018-12-13 13:08:14
• 更新时间：2026-07-07 13:36:20

名称

• 中文名: 2-脱氧-2,2-二氟-呋喃核糖基-3,5-二苯甲酰基-1-甲磺酸酯
• 英文名: ((2R,3R,5S)-3-(Benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate
• 中文别名: 2-脱氧-2,2-二氟-ALPHA-D-赤式-呋喃戊糖 3,5-二苯甲酸酯 1-甲烷磺酸酯; ((2R,3R,5R)-3-(苯甲酰氧基)-4,4-二氟-5-((甲基磺酰基)氧基)四氢呋喃-2-基)苯甲酸甲酯; ALFA呋喃核糖磺酸酯; Elab Fluor 647 标记抗小鼠CD8a 抗体YTS 105.18]-AN00331UM; FITC 标记抗小鼠CD8a 抗体YTS 105.18]-AN00331UC; 2-脱氧-2,2-二氟-D-呋喃核糖基-3,5-二甲苯酰基-1-甲磺酸酯(Α型); Elab FluorViolet 540 标记抗小鼠CD8a 抗体53-6.7]-E-AB-F1104T3; 2,2-二氟-3,5-二苯甲酰基-呋喃核糖; Per标记抗小鼠CD8a 抗体YTS 105.18]-AN00331UF; Purified 标记抗小鼠CD8a 抗体YTS169.4]-AN004080P; 呋喃内酯ALTA异构体; PE/Elab Fluor 594 标记抗小鼠CD8a 抗体53-6.7]-E-AB-F1104P; Elab Fluor 488 标记抗小鼠CD8a 抗体53-6.7]-E-AB-F1104UL; Elab Fluor 488 标记抗小鼠CD8a 抗体YTS 105.18]-AN00331L; Elab Fluor 488 标记抗小鼠CD8a 抗体YTS 105.18]-AN00331UL; PE/Elab Fluor 594 标记抗小鼠CD8 抗体YTS-169]-AN00576P; APC 标记抗小鼠CD8a 抗体YTS 105.18]-AN00331UE; Per标记抗小鼠CD8a 抗体53-6.7]-E-AB-F1104UF; 2-脱氧-2,2-二氟-D-呋喃核糖基-3,5-二苯甲酰基-1-甲磺酸; Elab Fluor Red 780 标记抗小鼠CD8a 抗体53-6.7]-E-AB-F1104US; PE/Elab Fluor 594 标记抗小鼠CD8a 抗体2.43]-E-AB-F9996P; APC 标记抗小鼠CD8a 抗体2.43]-E-AB-F9996E; Per/Cyanine5.5 标记抗小鼠CD8a 抗体YTS 105.18]-AN00331UJ; ((2R,3R,5R)-3-(苯并基氧基)-4,4-二氟-5-((甲基磺酰基)氧基)四氢呋喃-2-基) 苯甲酸甲酯; 吉西他滨杂质4 ALFA呋喃核糖磺酸酯; Per/Cyanine5.5 标记抗小鼠CD8a 抗体YTS 105.18]-AN00331J; Per标记抗小鼠CD8a 抗体YTS 105.18]-AN00331F; 2-脱氧-2,2-二氟-D-呋喃核糖基-3,5-二甲苯酰基-1-甲磺酸酯; PE/Cyanine5.5 标记抗小鼠CD8a 抗体53-6.7]-E-AB-F1104UI; 2-脱氧-2,2-二氟-alpha-D-赤式-呋喃戊糖 3,5-二苯甲酸酯 1-甲烷磺酸酯; 2-脱氧-2,2-二氟-D-呋喃核糖基-3,5-二甲苯酰基-1-甲磺酸酯(Α型)吉西他滨中间体; ALPHA-2-脱氧-2,2-二氟-D-呋喃核糖基-3,5-二苯甲酰基-1-甲磺酸酯; Elab Fluor 647 标记抗小鼠CD8a 抗体53-6.7]-E-AB-F1104UM; AF/LE Purified 标记抗小鼠CD8a 抗体YTS169.4]-AN; Purified 标记抗小鼠CD8a 抗体YTS 105.18]-AN003310P; Elab Fluor 647 标记抗小鼠CD8a 抗体YTS 105.18]-AN00331M; 重组 Mouse CD8a/Lyt2蛋白(truncated) (His标签)-PDMM100021; Elab FluorViolet 540 标记抗小鼠CD8a 抗体53-6.7]-E-AB-F1104UT3; 2-脱氧-2,2-五呋喃糖; FITC 标记抗小鼠CD8a 抗体YTS 105.18]-AN00331C; Elab Fluor 488 标记抗小鼠CD8a 抗体53-6.7]-E-AB-F1104L; 吉西他滨中间体 2-脱氧-2,2-二氟-D-呋喃核糖基-3,5-二苯甲酰基-1-甲磺酸酯; APC 标记抗小鼠CD8a 抗体YTS 105.18]-AN00331E; 2-脱氧-2,2-二氟-Α-D-呋喃核糖基-3,5-二苯甲酰基-1-甲磺酸酯; 2-脱氧-2,2-二氟-D-呋喃核糖基-3,5-二甲苯酰基-1-甲; PE/Elab Fluor 594 标记抗小鼠CD8a 抗体53-6.7]-E-AB-F1104UP; PE 标记抗小鼠CD8a 抗体YTS 105.18]-AN00331UD
• 英文别名: Benzoic acid, 2-[(2R,3R,5R)-3-(benzoyloxy)-4,4-difluorotetrahydro-5-[(methylsulfonyl)oxy]-2-furanyl]-, methyl ester; 2-Deoxy-2,2-difluoro-3,5-dibenzoate-1-methanesulfonate α-D-erythro-Pentofuranose; 2-Deoxy-2,2-difluoro-alpha-D-erythro-pentofuranose 3,5-dibenzoate 1-Methanesulfonate; Ly-B; 3,5-Bis(benzoyl)-1-methanesulfonyloxy-2-deoxy-2,2-difluorori; 3-(Benzoyloxy); 4,4-difluoro-5-((methylsulfonyl); 2-Deoxy-2,2-difluoro-D-ribofuranosyl-3,5-dibenzoyl-1-methanesulfonate; Lyt2; ((2R,3R,5S)-3-(Benzoyloxy)-4,4-difluoro-5-((methyl-sulfonyl)oxy)tetrahydrofuran-2-yl)methyl be; ((2R,3R,5R)-3-(Benzoyloxy)-4,4-difluoro-5-((Methylsulfonyl)oxy)tetrahydrofuran-2-yl)Methyl benzoate; ((2R,3R,5R)-3-(benzoyloxy); α-D-erythro-Pentofuranose, 2-deoxy-2,2-difluoro-, 3,5-dibenzoate 1-methanesulfonate; Gemcitabine impurity 2/2-Deoxy-2,2-difluoro-3,5-dibenzoate-1-methanesulfonate α-D-erythro-Pentofuranose; Ly-35; ((2R,3R,5S)-3-(Benzoyloxy)-4,4-difluoro-5-((methyl-sulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzo; ((2R,3R,5S)-3-(Benzoyloxy)-4,4-difluoro-5-((methyl-sulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate; 2-Deoxy-2,2-difluoro-alpha-D-erythro-pentofuranose 3,5-dibenzoate 1-methanesulfonate; Lyt-2; 3,5-Bis(benzoyl)-1-methanesulfonyloxy-2-deoxy-2,2-difluororibose(α-form); 3,5-Di-O-benzoyl-2-deoxy-2,2-difluoro-1-O-(methylsulfonyl)-D-erythro-pentofuranose; 3,5-Di-O-benzoyl-2-deoxy-2,2-difluoro-1-O-methanesulfonyl-a-D-ribofuranoside - alpha purity; 3,5-di-O-benzoyl-2-deoxy-2,2-difluoro-1-O-methanesulfonyl-α-D-ribofuranoside; ((2R,3R,5S)-3-(benzoyloxy)-4,4-difluoro-5-((Methylsulfonyl)oxy)tetrahydrofuran-2-yl)Methyl benzoate; Ly-2; 134-2 2-Deoxy-2,2-difluoro-D-ribofuranose-3,5-dibenzoate-1-methanesulfonate; 2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate; D-erythro-Pentofuranose, 2-deoxy-2,2-difluoro-, 3,5-dibenzoate 1-methanesulfonate; Methyl 2-{(2R,3R,5R)-3-(benzoyloxy)-4,4-difluoro-5-[(methylsulfonyl)oxy]tetrahydro-2-furanyl}benzoate; alpha-2-deoxy-2,2-difluoro-D-ribofuranose-3,5-dibenzoate-1-methanesulfonate

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 588.5±50.0 °C at 760 mmHg
• 分子式: C₂₀H₁₈F₂O₈S
• 分子量: 456.414
• 闪点: 309.7±30.1 °C
• 精确质量: 456.069031
• PSA: 113.58000
• LogP: 4.35
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.574
• 储存条件: 室温，干燥

安全

• 危害码 (欧洲): Xi

合成路线

124-63-0 1173824-58-2 ~99% 134877-42-2

文献：Quintiliani, Maurizio; Persoons, Leentje; Solaroli, Nicola; Karlsson, Anna; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan; McGuigan, Christopher Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 14 p. 4338 - 4345

122111-01-7 ~% 134877-42-2

文献：Synthesis, , # 6 p. 565 - 570

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