5985-28-4

• 常用中文名：辛弗林盐酸盐
• 常用英文名：Synephrine hydrochloride
• CAS号：5985-28-4
• 分子式：C₉H₁₄ClNO₂
• 分子量：203.666
• 相关类别： 生物化工 抑制剂 神经信号通路(Neuronal Signaling) Adrenergic Receptor 激动剂
• 发布时间：2018-04-23 08:00:00
• 更新时间：2026-08-02 06:59:40
• Synephrine(Oxedrine)盐酸盐是生物碱,是肾上腺素受体激动剂。

名称

• 中文名: 辛弗林盐酸盐
• 英文名: 4-[1-hydroxy-2-(methylamino)ethyl]phenol,hydrochloride
• 中文别名: 盐酸盐辛佛宁; 4-[1-羟基-2-(甲氨基)乙基]苯酚盐酸盐; 辛弗林盐酸盐/盐酸辛弗林/新福林盐酸盐; 1-(4-羟基苯基)-2-(甲基氨基)-乙醇盐酸盐; 辛弗林盐酸盐(标准品); 辛氟林酸盐; 辛弗林盐酸盐,10 MM DMSO 溶液; 氯化[2-羟基-2-(4-羟苯基)乙基]-甲基-铵; 氯化[2-羟基-2-(4-羟苯基)乙基]-甲基铵; 辛弗林盐酸盐 MIN; 对-甲基氨基乙醇苯酚盐酸盐; 辛弗林盐酸盐/盐酸辛弗林; 4-[1-羟基-2-(甲基氨基)乙基]苯酚2,3-二羟基琥珀酸盐(盐); 盐酸肾上腺素杂质G; 辛弗林盐酸; 盐酸辛弗林, 是衍生自柑橘类植物的 Α-ADRENERGIC 和 -ADRENERGIC 激动剂,与麻黄和麻黄碱生物碱具有拟交感神经和结构相似性
• 英文别名: p-hydroxy-alpha-((methylamino)methyl)-benzylalcohohydrochloride; SYNHRINE HYDROCHLORIDE; Benzenemethanol, 4-Hydroxy-α-((methylamino)methyl)-,hydrochloride; 4-Hydroxy-α-[(MethylaMino)Methyl]benzeneMethanol Hydrochloride; (±)-p-Hydroxynorhedrine hydrochloride; Synephrine HCl; 4-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride; Synhrine hydrochloride //BP; p-Methylaminoaethanolphenol hydrochlorid [German]; Synhrine hydrochlorid; UNII-EN5D1IH09S; Supply High Quality Synhrine hydrochloride powder CAS NO.:5-4 CAS NO.5-4; Synhrine hydrochloride an α-adrenergic and -adrenergic agonist derived from the Citrus aurantium, it has sympathomimetic and structural similities to hedra and hedrine alkaloids; J-5985; Oxedrine hydrochloride; 1-(4-Hydroxy-phenyl)-2-methylamino-aethanol,Hydrochlorid; 4-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol hyd; SYNHRINE HCL; top quality Synhrine hydrochloride; SYNHRINE HYDROCHLORIDE; OXEDRINE HYDROCHLORIDE; 2-methylamino-1-(4-hydroxyphenyl)-ethanol hydrochloride; (±)-Synhrine (hydrochloride); [2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methylazanium chloride; rac-Synhrine Hydrochloride; p-methylaminoethanolphenolhydrochloride; Phmaceutical Intermediate CAS5-4Synhrine Hydrochloride Synhrine HCl; Synhrine hydrochloride, 10 mM in DMSO; p-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride; 4-[1-hydroxy-2-(MethylaMino)ethyl]phenol hydrochloride; 4-[1-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride (1:1); Benzenemethanol, 4-hydroxy-α-[(methylamino)methyl]-, hydrochloride (1:1); p-hydroxy-alpha-(methylaminomethyl)benzylalcoholhydrochloride; Sympathol hydrochloride; [2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methylammonium chloride; [2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methyl-ammonium chloride; Benzenemethanol, 4-hydroxy-a-[(methylamino)methyl]-, hydrochloride; (+-)-1-(4-hydroxy-phenyl)-2-methylamino-ethanol,hydrochloride; Ocuton (TN); 4-hydroxy-alpha-((methylamino)methyl)-benzenemethanohydrochloride; (±)-Oxedrine hydrochloride; UNII:EN5D1IH09S; 4-hydroxy-alpha-[(methylamino)methyl]benzyl alcohol hydrochloride; 4-[1-hydroxy-2-(methylamino)ethyl]phenol 2,3-dihydroxysuccinate (salt); DL-synephrine hydrochloride; EINECS 227-804-6; Synhrine HCl min; (+)p-synhrine hydrochloride; 1-(4-Hydroxyphenyl)-2-(methylamino)-ethanol hydrochloride; l-1-p-hydroxyphenyl-2-methylamino-1-ethanolhydrochloride; MFCD00050566; SYNHRINE HYDROCHLORIDE MIN; dl-p-Hydroxynorhedrine hydrochloride; Synhrine/Synhrine Hcl; p-methylaminoaethanolphenolhydrochlorid; N-METHYL OCTOPAMINE HCL; [2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methyl-azanium chloride

物化性质

• 沸点: 341.1ºC at 760 mmHg
• 熔点: 147-150ºC
• 分子式: C₉H₁₄ClNO₂
• 分子量: 203.666
• 闪点: 163.4ºC
• 精确质量: 203.071304
• PSA: 52.49000
• LogP: 1.83790
• 外观性状: 白色细粉末
• 储存条件: Refrigerator

生物活性

• 描述: Synephrine(Oxedrine)盐酸盐是生物碱,是肾上腺素受体激动剂。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体
  天然产物 >> 生物碱
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Synephrine, From Wikipedia

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DO7700000 CHEMICAL NAME : Benzyl alcohol, p-hydroxy-alpha-((methylamino)methyl)-, hydrochloride CAS REGISTRY NUMBER : 5985-28-4 LAST UPDATED : 199712 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C9-H13-N-O2.Cl-H MOLECULAR WEIGHT : 203.69 WISWESSER LINE NOTATION : QR DYQ1M1 &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 320 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 71,62,1941 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 124,231,1927 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 124,231,1927

安全

• 危害码 (欧洲): Xi
• 海关编码: 2922199090

上下游产品

上游产品  0
下游产品  1
14593-25-0

海关

海关编码	2922509090
中文概述	2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	R.进口食品卫生监督检验 S.出口食品卫生监督检验
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%