苯磺酸左旋氨氯地平

• 常用名: 苯磺酸左旋氨氯地平
• 英文名: Levamlodipine
• CAS号: 103129-82-4
• 分子量: 567.051
• 密度: 1.2±0.1 g/cm3
• 沸点: 527.2±50.0 °C at 760 mmHg
• 分子式: C₂₀H₂₅ClN₂O₅
• 熔点: 102-104°C
• 闪点: 272.6±30.1 °C

苯磺酸左旋氨氯地平用途

Levamlodipine ((S)-Amlodipine) 是一种功能强大的二氢吡啶钙通道阻滞剂,具有舒张血管的作用,可用于高血压、心绞痛的治疗。

苯磺酸左旋氨氯地平名称

• 中文名: 左旋氨氯地平
• 英文名: (S)-Amlodipine
• 中文别名: s-氨氯地平 | (4S)-2-[(2-氨基乙氧基)甲基]-4-(2-氯苯基)-1,4-二氢-6-甲基-3,5-吡啶二甲酸 3-乙基 5-甲基酯 | (S)-氨氯地平 | 苯磺酸左旋氨氯地平

苯磺酸左旋氨氯地平生物活性

• 描述: Levamlodipine ((S)-Amlodipine) 是一种功能强大的二氢吡啶钙通道阻滞剂,具有舒张血管的作用,可用于高血压、心绞痛的治疗。
• 相关类别:
  信号通路 >> 跨膜转运 >> 钙通道
  研究领域 >> 其他
• 靶点实验:

  Calcium channel[1].

• 参考文献:

  [1]. Jain R, et al. Polyaniline-graphene oxide nanocomposite sensor for quantification of calcium channel blocker levamlodipine. Mater Sci Eng C Mater Biol Appl. 2016 Aug 1;65:205-14.

苯磺酸左旋氨氯地平物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 527.2±50.0 °C at 760 mmHg
• 熔点: 102-104°C
• 分子式: C₂₀H₂₅ClN₂O₅
• 分子量: 567.051
• 闪点: 272.6±30.1 °C
• 精确质量: 566.148987
• PSA: 99.88000
• LogP: 4.16
• InChIKey: HTIQEAQVCYTUBX-KRWDZBQOSA-N
• SMILES: CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1c1ccccc1Cl
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.546
• 储存条件: -20°C Freezer

苯磺酸左旋氨氯地平安全信息

• 危害码 (欧洲): Xi

苯磺酸左旋氨氯地平靶点实验

查看更多实验

实验名称：Binding affinity towards human ADRA2A in an in vitro assay with cellular components m... 来源：ChEMBL 靶标：Alpha-2A adrenergic receptor External Id：CHEMBL5291736

实验名称：Binding affinity towards human GABRA1 in an in vitro assay with cellular components m... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit gamma-2 External Id：CHEMBL5291799

实验名称：Binding affinity towards human PGR in an in vitro assay with cellular components meas... 来源：ChEMBL 靶标：Progesterone receptor External Id：CHEMBL5291863

实验名称：Binding affinity towards human ESR1 in an in vitro cell free assay (CRO assay) measur... 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL5291792

实验名称：Binding affinity towards human ADORA3 (agonistic activity) in an in vitro assay with ... 来源：ChEMBL 靶标：Adenosine receptor A3 External Id：CHEMBL5291728

实验名称：Compound was evaluated for inhibition of human PDE3A in an in vitro cell free assay m... 来源：ChEMBL 靶标：cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A External Id：CHEMBL5291856

实验名称：Binding affinity towards human OPRM1 in an in vitro assay with cellular components me... 来源：ChEMBL 靶标：Mu-type opioid receptor External Id：CHEMBL5291855

实验名称：Agonist activity at human ADRA1A in an in vitro cell-based assay (CRO assay) measured... 来源：ChEMBL 靶标：Alpha-1A adrenergic receptor External Id：CHEMBL5291730

实验名称：Compound was evaluated for inhibition of human F2 in an in vitro cell free assay meas... 来源：ChEMBL 靶标：Prothrombin External Id：CHEMBL5291794

实验名称：Compound was evaluated for inhibition of human PDE4A in an in vitro cell free assay m... 来源：ChEMBL 靶标：3',5'-cyclic-AMP phosphodiesterase 4A External Id：CHEMBL5291857

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苯磺酸左旋氨氯地平英文别名

• Norvasc
• 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4S)-, benzenesulfonate (1:1)
• l-Amlodipine
• Levamlodipine Besylate Tablets
• LevoaMlodipine
• 3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
• T6M DHJ B1O2Z CVO2 DR BG& EVO1 F1
• 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl Ester
• Lodien
• UNII:1J444QC288
• 3-Ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• Levamlodipine
• 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
• 3-Ethyl 5-methyl (4S)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate benzenesulfonate (1:1)
• Amlodipine
• Levoamlodipine Besylate
• 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• 3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate