香蒲新苷

• 常用名: 香蒲新苷
• 英文名: Typhaneoside
• CAS号: 104472-68-6
• 分子量: 770.685
• 密度: 1.7±0.1 g/cm3
• 沸点: 1065.0±65.0 °C at 760 mmHg
• 分子式: C₃₄H₄₂O₂₀
• 熔点: N/A
• 闪点: 332.6±27.8 °C

香蒲新苷用途

Typhaneoside,从香蒲 (Typha angustifolia L.) 中提取,可抑制缺氧/复氧细胞的过度自噬 (autophagy) 并增加 Akt 和 mTOR 的磷酸化。Typhaneoside 对心血管系统有一定的作用,包括降低血脂水平,促进抗动脉粥样硬化活动,以及提高免疫和凝血功能。

香蒲新苷名称

• 中文名: 香蒲新苷
• 英文名: 3-[(3R,4S,5S,6R)-4,5-dihydroxy-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one
• 中文别名: 香蒲新甙

香蒲新苷生物活性

• 描述: Typhaneoside,从香蒲 (Typha angustifolia L.) 中提取,可抑制缺氧/复氧细胞的过度自噬 (autophagy) 并增加 Akt 和 mTOR 的磷酸化。Typhaneoside 对心血管系统有一定的作用,包括降低血脂水平,促进抗动脉粥样硬化活动,以及提高免疫和凝血功能。
• 相关类别:
  研究领域 >> 心血管疾病
  信号通路 >> 自噬 >> 自噬
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Zhang X, et al. Effect of typhaneoside on ventricular remodeling and regulation of PI3K/Akt/mTOR pathway. Herz. 2019 Jun 14.

香蒲新苷物理化学性质

• 密度: 1.7±0.1 g/cm3
• 沸点: 1065.0±65.0 °C at 760 mmHg
• 分子式: C₃₄H₄₂O₂₀
• 分子量: 770.685
• 闪点: 332.6±27.8 °C
• 精确质量: 770.226929
• PSA: 317.35000
• LogP: 2.27
• InChIKey: POMAQDQEVHXLGT-QQVXUORWSA-N
• SMILES: COc1cc(-c2oc3cc(O)cc(O)c3c(=O)c2OC2OC(COC3OC(C)C(O)C(O)C3O)C(O)C(O)C2OC2OC(C)C(O)C(O)C2O)ccc1O
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.716
• 储存条件: 2~8°C

香蒲新苷安全信息

• 危害码 (欧洲): Xi

香蒲新苷靶点实验

查看更多实验

实验名称：Cytotoxicity against human Raji cells assessed as cell viability at 10 molar ratio 来源：ChEMBL 靶标：Raji External Id：CHEMBL977475

实验名称：Cytotoxicity against human Raji cells assessed as cell viability at 100 molar ratio 来源：ChEMBL 靶标：Raji External Id：CHEMBL977474

实验名称：Inhibition of TPA-induced EBV-early antigen activation in human Raji cells relative t... 来源：ChEMBL 靶标：N/A External Id：CHEMBL976634

实验名称：Antineuroinflammatory activity in mouse N9 cells assessed as inhibition of LPS-induce... 来源：ChEMBL 靶标：N9 External Id：CHEMBL4001903

实验名称：Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 10 mola... 来源：ChEMBL 靶标：N/A External Id：CHEMBL976633

实验名称：Cytotoxicity against human Raji cells assessed as cell viability at 500 molar ratio 来源：ChEMBL 靶标：Raji External Id：CHEMBL977473

实验名称：Cytotoxicity against human Raji cells assessed as cell viability at 1000 molar ratio 来源：ChEMBL 靶标：Raji External Id：CHEMBL976635

实验名称：Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 1000 mo... 来源：ChEMBL 靶标：N/A External Id：CHEMBL976630

实验名称：Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 100 mol... 来源：ChEMBL 靶标：N/A External Id：CHEMBL976632

实验名称：Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 500 mol... 来源：ChEMBL 靶标：N/A External Id：CHEMBL976631

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香蒲新苷英文别名

• I07-0144
• Typhaneoside
• 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-4H-chromen-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-(1->6)]-β-D-glucopyranoside
• N1474
• isorhamnetin 3-O-2G-rhamnosylrutinoside